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Database: UniProt
Entry: H3DKB5_TETNG
LinkDB: H3DKB5_TETNG
Original site: H3DKB5_TETNG 
ID   H3DKB5_TETNG            Unreviewed;      1540 AA.
AC   H3DKB5;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   26-FEB-2020, entry version 47.
DE   SubName: Full=Ankyrin 2a, neuronal {ECO:0000313|Ensembl:ENSTNIP00000020961};
OS   Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS   nigroviridis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX   NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000020961, ECO:0000313|Proteomes:UP000007303};
RN   [1] {ECO:0000313|Ensembl:ENSTNIP00000020961}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15496914; DOI=10.1038/nature03025;
RA   Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA   Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA   Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA   Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA   Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA   Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA   Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA   McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA   Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA   Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA   Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT   "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT   early vertebrate proto-karyotype.";
RL   Nature 431:946-957(2004).
RN   [2] {ECO:0000313|Ensembl:ENSTNIP00000020961}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   Ensembl; ENSTNIT00000021194; ENSTNIP00000020961; ENSTNIG00000017807.
DR   GeneTree; ENSGT00940000155279; -.
DR   HOGENOM; CLU_000134_7_1_1; -.
DR   Proteomes; UP000007303; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.25.40.20; -; 3.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR040745; Ankyrin_UPA.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   InterPro; IPR000906; ZU5_dom.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 6.
DR   Pfam; PF00531; Death; 1.
DR   Pfam; PF17809; UPA_2; 1.
DR   Pfam; PF00791; ZU5; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 23.
DR   SMART; SM00005; DEATH; 1.
DR   SMART; SM00218; ZU5; 1.
DR   SUPFAM; SSF47986; SSF47986; 1.
DR   SUPFAM; SSF48403; SSF48403; 3.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 21.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
DR   PROSITE; PS51145; ZU5; 2.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT   DOMAIN          25..800
FT                   /note="ANK_REP_REGION"
FT                   /evidence="ECO:0000259|PROSITE:PS50297"
FT   REPEAT          58..90
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          91..123
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          124..156
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          157..180
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          219..251
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          252..284
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          285..317
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          318..350
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          351..383
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          384..416
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          417..449
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          450..482
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          483..515
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          516..548
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          549..581
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          582..614
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          615..647
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          648..680
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          681..713
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          714..746
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          747..779
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          965..1120
FT                   /note="ZU5"
FT                   /evidence="ECO:0000259|PROSITE:PS51145"
FT   DOMAIN          1122..1270
FT                   /note="ZU5"
FT                   /evidence="ECO:0000259|PROSITE:PS51145"
FT   DOMAIN          1459..1540
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1199..1218
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1202..1218
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1540 AA;  169393 MW;  4903EB6A6762AB03 CRC64;
     RAREKRRQQR ERAERKRQSS HLQSDSNTSF LRAARAGNID KVLDFLKNGI DISTCNQNGL
     NALHLAAKEG HKDLVEELLD RGAPVDSSTK KGNSALHIAS LAGQKEVVRL LVKRGANINS
     QSQNGFTPLY MAAQENHLEV VRYLLENDGN QSIATEDGFT PLAIALQQGH NSVVSLLLEH
     DTKGKVRLPA LHIAARKDDT KSAALLLQND HNADVQSKSG FTPLHIAAHY GNVNVSTLLL
     NRGAAVDFTA RNGITPLHVA SKRGNTNMVA LLLDRGAQID AKTRDGLTPL HCAARSGHDQ
     AVEILLDRGA PILARTKNGL SPLHMSAQGD HIECVKLLLQ HQAPVDDVTL DYLTALHVAA
     HCGHYRVTKL LLDKKANPNV RALNGFTPLH IACKKNRVKV MELLVKYGAS IQAITESGLT
     PIHVAAFMGH LSIVLLLLQN GASPDIRNIR GETALHMAAR AGQMEVVRCL LRNGALVDAM
     AREDQTPLHI ASRLGKTDIV QLLLQHMAHP DAATTNGYTP LHISAREGQL ETAAVLLEAG
     ASHSLPTKKG FTPLHVAAKY GNLDVAKLLL QSKALPDDAG KNGLTSLHVA AHYDNQDVAL
     LLLDKGASPH STAKNGYTPL HIAAKKNQTK IASALLQYGA ETNILTKQGV SPLHLAAQEG
     HTEMTGLLLD KGAHVNAATK SGLTPLHLTA QEDKVGAAEV LAKYDANLDQ QTKLGYTPLI
     VACHYGNAKM VNFLLQQGAS VNAKTKNGYT PLHQAAQQGN THIINVLLQH GAKPNTTTMS
     GNTALSIARR LGYISVVDTL KVVTEEVITT TTTVTEKHKL NVPETMTEVL DVSDEEALKL
     EDEPLTEMSV ELEGEDTMTG DGGEYLRAED LRDLGDDSLP GHYLDFRQVE IGQTDKQMRR
     FGTSQHTPIH QSFTQREGFF IEDMLTSHQV SVLSKEHEKD SFRLSWGAEH LDNVVLSSSL
     LHSGFLVSFM VDARGGAMRG CRHNGLRIIV PPRKCSAPTR VTCRLVKRHR LASMPPMVEG
     EGLAGRIIEV GPTGAQFLGP VIVEIPHFAA LRGTERELVI LRSETGESWR EHHCDFTEEE
     LNQILNGMDE KLDSPEELEK KRICRIITRD FPQYFAVVSR IKQDSHLIGP EGGVLSSTLV
     PQVQAVFPEG ALTKKIRVGL QAQPIDGDVV KKILGNKAAF SAIVTLEPRR RKFHKPITMT
     IPIPKSPNTE GPTSEFSGET PTLRLLCSIT GGTTPAQWED ITGSTPLTFV NHCVSFTTNV
     SARFWLIDCR QVQESVSFAS QLYREIICVP YMAKFVIFAK TLDPIEARLR CFCMTDDKMD
     KTLEQQENFT EVARSRDVEV LEGKPIFVDC FGNLVPLTKS GQHHVFSFFA FKENRLALFI
     KIRDTAQEPC GRLSFTKEAR TYRSLTHNAI CNLNITLPAY SKSEKSEKKF KLGLFLIKSK
     HASITEPQLQ SGQDPLKSKE ETLTIIADLL GFSWTELAKE LEFSENDIQS VRTDNPNSLQ
     EQSHALLQRW VEREGKHATE DCLIKTLTKI NRMDIVHLIE
//
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