ID H3DML7_TETNG Unreviewed; 1038 AA.
AC H3DML7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=BAI1 associated protein 3 {ECO:0000313|Ensembl:ENSTNIP00000021765.1};
GN Name=BAIAP3 {ECO:0000313|Ensembl:ENSTNIP00000021765.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000021765.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000021765.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the unc-13 family.
CC {ECO:0000256|ARBA:ARBA00005823}.
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DR AlphaFoldDB; H3DML7; -.
DR Ensembl; ENSTNIT00000022000.1; ENSTNIP00000021765.1; ENSTNIG00000018591.1.
DR GeneTree; ENSGT00730000110939; -.
DR HOGENOM; CLU_003295_2_0_1; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR CDD; cd08676; C2A_Munc13-like; 1.
DR CDD; cd04009; C2B_Munc13-like; 1.
DR Gene3D; 1.10.357.50; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR010439; MUN_dom.
DR InterPro; IPR014770; Munc13_1.
DR InterPro; IPR014772; Munc13_dom-2.
DR PANTHER; PTHR45999:SF1; BAI1-ASSOCIATED PROTEIN 3; 1.
DR PANTHER; PTHR45999; UNC-13-4A, ISOFORM B; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF06292; MUN; 1.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS51258; MHD1; 1.
DR PROSITE; PS51259; MHD2; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT DOMAIN 42..221
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 517..637
FT /note="MHD1"
FT /evidence="ECO:0000259|PROSITE:PS51258"
FT DOMAIN 750..858
FT /note="MHD2"
FT /evidence="ECO:0000259|PROSITE:PS51259"
FT DOMAIN 873..998
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
SQ SEQUENCE 1038 AA; 119519 MW; F8B8B755DC0780AA CRC64;
QLDLLYEEAV YTVVHRVGVP SSEHVKSDEE LFAYLLKVFD MGEEEHEIIL QKVQEAKRAS
FSLRVSVMKA KNLMAKDANG YSDPYCMLGI LVGQSPREMK RKEKLEKRSS TKEVLPARSI
QVTEVKPETL NPVWDEHFVF EIDDVNNDLL HLDIWDHDDD VSVAEACKKL NEVSGLRGMI
AKSVRANGST SSGSEENADD FLGCINIPLN EMPVGGYDTW FKLEPRSSTS KVQGECHLIL
KLFTNQRDTT LSKKDSNIAI HRKLLTQILE YDHSQVKREP YNWNGQVCPA AWTVLTHHAV
QTDLPPLQQA IIRWQCYSSH HRTQRVCYSL LLRLLRTIDA GWDPTVVRGD LERQLSDSFR
LYTEHCLCLM KNMRQVFPCA SAAAIARFEL MLRGIGYMQN MRAFKSVCPL RNELHLDITT
AVKKGSAEWY EGLIARYKPE EGSLEEQLKK LVQIVDCVCA DVQQAQNVYN KLFYSTVKVD
FLSISYRQLE NVAMERVCGT LEQESSRLTQ PIGETIFELF ISLKILKGFR EFLPLKDAKM
LALTGFHNWF KTPIHKWLQI VHDRSCDRIS KAVEMDKLEP VQQEKHSSSA VEVAACFGQV
RKIWLQLAWP DSAGAFIFIT RLTDNFCSEA VCYSEMMTRR IERNQLGRDY KSFTVQLCIA
LNSMEHVRVF LTHLPRDLDW QGVERAMEEA CGLEGKEQVY KALNGQLFNM DLDLQREAKH
LITLLTEKMQ PELRRYIQHI SLSPDSINND DAVSPLMKYL QDTSAILTEN LVKENLTRVL
QSMWELLVRM ILDALTENRG VQVEFYNRFQ YTVETLLQFF HARGEGLSVD DMKSGDYKVL
DEELRLNKCS SFELIEQYYL EKISHQKTLK HTRYGRISVK CYYDAPEQRL TVEILHAADI
MALDANGLSD PFVIVELCPH HLFPMAKSQR TQVKLKTLHP VFDELFYFHV SPEHYRHRFA
CLTFTVMDYD WLSTNDFAGE AVAPLSDFCW PGRPNASPAG KSVQPVILHL SRSKPSEKPI
MRMLDARVGD REAQEFVR
//
