ID H3DMR3_TETNG Unreviewed; 457 AA.
AC H3DMR3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Vimentin like {ECO:0000313|Ensembl:ENSTNIP00000021811.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000021811.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000021811.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Vimentins are class-III intermediate filaments found in
CC various non-epithelial cells, especially mesenchymal cells. Vimentin is
CC attached to the nucleus, endoplasmic reticulum, and mitochondria,
CC either laterally or terminally. {ECO:0000256|ARBA:ARBA00002825}.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR AlphaFoldDB; H3DMR3; -.
DR STRING; 99883.ENSTNIP00000021811; -.
DR Ensembl; ENSTNIT00000022047.1; ENSTNIP00000021811.1; ENSTNIG00000018636.1.
DR GeneTree; ENSGT00940000156146; -.
DR HOGENOM; CLU_012560_7_4_1; -.
DR InParanoid; H3DMR3; -.
DR OMA; EMLEFQS; -.
DR TreeFam; TF330122; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR006821; Intermed_filament_DNA-bd.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF5; VIMENTIN; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF04732; Filament_head; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT DOMAIN 95..402
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 99..235
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 307..380
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 457 AA; 53278 MW; C8759B0FEACF98AE CRC64;
KKKKMTQRPT PHSSYKRMFG GDRVVSRTSY SSRQFSSPLR SSRVSYSLSS APAVYALKTQ
RLRSSSAMPR LASENLDFSL SDAINTEFIT NRTNEKAQMQ SLNDRFASYI EKVRFLEQQN
KILLAEEQLR GKGTSRVGDL YEDEMRDLRR QVDQLTNEKA RVEVHRDNLV DDIERLREKL
QDEIGQREEA ENNMQSFRQD VDNAALARLD LERKVESLQE EINFLKKLHD EEMLELQNQM
HQQQHVQVDM EMAKPDLTAA LRDVRLQYEN LASKNIQESE EWYKSKFADL TEAAARNNDA
LRVAQEANDY RRQVQALTCE VDALKGTNES LERQMREMEE NFSLENGGYQ DSIRQLEEDI
HNMKDEMARH LREYQDLLNV KMALDIEIAT YRKLLEGEES RISTPLPSFS SLNLRETMIE
PKPHIETTTT KKVLIKTIET RDGQVINEST QNHDDME
//
