ID H3G7G7_PHYRM Unreviewed; 653 AA.
AC H3G7G7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};
OS Phytophthora ramorum (Sudden oak death agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=164328 {ECO:0000313|EnsemblProtists:Phyra51456, ECO:0000313|Proteomes:UP000005238};
RN [1] {ECO:0000313|Proteomes:UP000005238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pr102 {ECO:0000313|Proteomes:UP000005238};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
RN [2] {ECO:0000313|EnsemblProtists:Phyra51456}
RP IDENTIFICATION.
RC STRAIN=Pr102 {ECO:0000313|EnsemblProtists:Phyra51456};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283,
CC ECO:0000256|RuleBase:RU000394}.
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DR EMBL; DS566003; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3G7G7; -.
DR STRING; 164328.H3G7G7; -.
DR EnsemblProtists; Phyra51456; Phyra51456; Phyra51456.
DR VEuPathDB; FungiDB:PSURA_51456; -.
DR eggNOG; KOG4280; Eukaryota.
DR HOGENOM; CLU_001485_22_4_1; -.
DR InParanoid; H3G7G7; -.
DR OMA; KQQVEYR; -.
DR Proteomes; UP000005238; Unassembled WGS sequence.
DR GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR GO; GO:0003777; F:microtubule motor activity; IBA:GO_Central.
DR GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47969; CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED; 1.
DR PANTHER; PTHR47969:SF15; ZGC:66125; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394}; Coiled coil {ECO:0000256|SAM:Coils};
KW Microtubule {ECO:0000256|RuleBase:RU000394};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW ECO:0000256|RuleBase:RU000394};
KW Reference proteome {ECO:0000313|Proteomes:UP000005238}.
FT DOMAIN 12..339
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 368..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 443..495
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 543..625
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 370..390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 96..103
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 653 AA; 72912 MW; 148B82E8FA96CB48 CRC64;
VPGTGGGKDK ETVKVVVRCR PLFGKELVEG RKSIVTLDSA AALISLKCPD NGQIKSFTFD
SVYDENTSQR QFYDESGYPL VESIFDGYNG TIFAYGQTGC GKTHTMQGKD SPPELRGVIP
LSFDHIFDTI NADTTREYMV RASYLEIYNE DIRDLLTDDA KKKLDLKESA DGTVYVKDLT
EIVVRDVDSM NNVMNRGFKN RTVGATLMNE GSSRSHSIFT VVVETSETIG GQDHFKAGKL
NLVDLAGSER QSKTGATGNR LKEGCKINLS LSALGNVISA LVDGKGKHIP YRDSKLTRLL
QDSLGGNTKT LMVAAVSPAD YNYDETLSTL RYANRAKNIK NKPIVNEDPK DAKLREYKEE
IERLRKMLES QSQSRGSGLG TASGMGTPSR PISPRSAIRE AAQIDAQAKA MMVKAEAMMK
EAAQREGAKQ TEVVVKEVIP ASHVKERDEL RELNQTILNQ RDRIGQELEQ TQVAMEAYLR
EKEMLHAKLK KIESHILGGA SSSSSTRGSV GGDADSEVAL LKQQVEYRRA QIKLREKAKK
QAKNEAVRRA LELEKQHVEE ELKTAQEAAQ ASLAAARKKE TKYRAKLEAT RQEIADLNSE
FERERENLLD TIREQTKEAK LLEQLVELFL PQNELVKVWE RAVWSEEREE WNL
//
