ID H3G849_PHYRM Unreviewed; 289 AA.
AC H3G849;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Enoyl-CoA hydratase {ECO:0008006|Google:ProtNLM};
OS Phytophthora ramorum (Sudden oak death agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=164328 {ECO:0000313|EnsemblProtists:Phyra71024, ECO:0000313|Proteomes:UP000005238};
RN [1] {ECO:0000313|Proteomes:UP000005238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pr102 {ECO:0000313|Proteomes:UP000005238};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
RN [2] {ECO:0000313|EnsemblProtists:Phyra71024}
RP IDENTIFICATION.
RC STRAIN=Pr102 {ECO:0000313|EnsemblProtists:Phyra71024};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|RuleBase:RU003707}.
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DR EMBL; DS565998; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3G849; -.
DR STRING; 164328.H3G849; -.
DR EnsemblProtists; Phyra71024; Phyra71024; Phyra71024.
DR VEuPathDB; FungiDB:PSURA_71024; -.
DR eggNOG; KOG1681; Eukaryota.
DR HOGENOM; CLU_009834_7_0_1; -.
DR InParanoid; H3G849; -.
DR OMA; QYVAHVE; -.
DR UniPathway; UPA00659; -.
DR Proteomes; UP000005238; Unassembled WGS sequence.
DR GO; GO:0051750; F:delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity; IBA:GO_Central.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR CDD; cd06558; crotonase-like; 1.
DR Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045002; Ech1-like.
DR InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR PANTHER; PTHR43149:SF1; DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43149; ENOYL-COA HYDRATASE; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE 3: Inferred from homology;
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000005238}.
SQ SEQUENCE 289 AA; 31492 MW; DACEFDBAC565F415 CRC64;
MAGPPQPLDV ASTKFDTLSL AFADDDAASG VLHLKLNRPK VVNAMNMQMW VELTRAFELV
ELDPSVRAVV VSGEGRGFTS GMDLDVFAQM QKVAMDESCE GRKRERLMRV IDKFQQIISA
PEKCRVPVIA AVHGPCIGAG VDFITACDLC YSDVSAIFSV KEVDLAIIAD VGTLQRLPKL
VGERQAKELA FTGRNFGGLE AEKLGLVLKA LPDHEALMNH VGDVAKSIAK KSPLTIRGIK
QTIHYQRDHS TADSLQQIRY HNAAVLYSDD LVQAVGALMN ATEPTFRSD
//
