ID H3GDB8_PHYRM Unreviewed; 613 AA.
AC H3GDB8;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=ZZ-type domain-containing protein {ECO:0000259|SMART:SM00291};
OS Phytophthora ramorum (Sudden oak death agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=164328 {ECO:0000313|EnsemblProtists:Phyra73545, ECO:0000313|Proteomes:UP000005238};
RN [1] {ECO:0000313|Proteomes:UP000005238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pr102 {ECO:0000313|Proteomes:UP000005238};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
RN [2] {ECO:0000313|EnsemblProtists:Phyra73545}
RP IDENTIFICATION.
RC STRAIN=Pr102 {ECO:0000313|EnsemblProtists:Phyra73545};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS566001; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3GDB8; -.
DR EnsemblProtists; Phyra73545; Phyra73545; Phyra73545.
DR VEuPathDB; FungiDB:PSURA_73545; -.
DR eggNOG; ENOG502QTPS; Eukaryota.
DR HOGENOM; CLU_017642_0_0_1; -.
DR InParanoid; H3GDB8; -.
DR OMA; CLTWIAD; -.
DR Proteomes; UP000005238; Unassembled WGS sequence.
DR GO; GO:0016235; C:aggresome; IBA:GO_Central.
DR GO; GO:0044753; C:amphisome; IBA:GO_Central.
DR GO; GO:0070530; F:K63-linked polyubiquitin modification-dependent protein binding; IBA:GO_Central.
DR GO; GO:0005080; F:protein kinase C binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0035973; P:aggrephagy; IBA:GO_Central.
DR GO; GO:0007032; P:endosome organization; IBA:GO_Central.
DR GO; GO:0000423; P:mitophagy; IBA:GO_Central.
DR Gene3D; 3.30.60.90; -; 1.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR15090; SEQUESTOSOME 1-RELATED; 1.
DR PANTHER; PTHR15090:SF0; SEQUESTOSOME-1; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005238};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 411..461
FT /note="ZZ-type"
FT /evidence="ECO:0000259|SMART:SM00291"
FT REGION 381..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 4..66
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 381..401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 613 AA; 66334 MW; 5A1EC9FB47AD4681 CRC64;
MLATATLQHN LAALQSQLGT LQQENSALSR DLCLKENYIQ LKDQQFRVMQ RRLEELEGAV
AQWKDRWLQQ VNAQHATSGE IGQVDRLEDA KWTPWKCKPG TTSRAKALAQ ASSKLEKLSQ
ADRNKLQPLL AAIEQSGQES GGDLGDLVFA DVSEELSRVL LLHLLPALVD AVDGAQQLQC
FSRTYRKQTM DFRVVVEAAE GDTAAAADKS PSGVVSVDAG GEVSVAVDLP EVEESEAPHL
FDWVELDRRG AGRSSVPHGP RELHATKAMF VSRPHSGSTA ARAVIPPLDK LGDKAQDKAS
RRYTLTPKRT GPTFAVETTR THTMTMGALP SPAQSPSSMG VLPLGSDGEV IPMPPREKEG
KDGKIKKIVG SVFDRLSRHK SLQSMGSNST TSSSSHASPV PLTAGSDAAG DEDESICDGC
GRGPLSGVKW VCRTCRLLAG EEYELCDKCY GQGLHGKEHE DALFARVEAI VVRKCPRLAS
ETELLHLLRV GICKANLKKF SFCLTWIADL LQCGRTTDLR ARALEIAHIP PTVRSEFARL
LRELLTRYRP DIELKTEWEP SAGAQHGTLG PGTPAMRGEG APDELDTLRI WVKDAPTANV
APTGATASGT SLG
//
