ID   H3GHG3_PHYRM            Unreviewed;       711 AA.
AC   H3GHG3;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
OS   Phytophthora ramorum (Sudden oak death agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=164328 {ECO:0000313|EnsemblProtists:Phyra75370, ECO:0000313|Proteomes:UP000005238};
RN   [1] {ECO:0000313|Proteomes:UP000005238}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pr102 {ECO:0000313|Proteomes:UP000005238};
RX   PubMed=16946064; DOI=10.1126/science.1128796;
RA   Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA   Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA   Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA   Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA   Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA   McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA   Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA   Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA   Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA   Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT   "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT   of pathogenesis.";
RL   Science 313:1261-1266(2006).
RN   [2] {ECO:0000313|EnsemblProtists:Phyra75370}
RP   IDENTIFICATION.
RC   STRAIN=Pr102 {ECO:0000313|EnsemblProtists:Phyra75370};
RG   EnsemblProtists;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; DS566009; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H3GHG3; -.
DR   EnsemblProtists; Phyra75370; Phyra75370; Phyra75370.
DR   VEuPathDB; FungiDB:PSURA_75370; -.
DR   eggNOG; KOG0017; Eukaryota.
DR   HOGENOM; CLU_000384_15_2_1; -.
DR   InParanoid; H3GHG3; -.
DR   OMA; HASASMN; -.
DR   Proteomes; UP000005238; Unassembled WGS sequence.
DR   CDD; cd00303; retropepsin_like; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR33064; POL PROTEIN; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF08284; RVP_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005238}.
FT   DOMAIN          376..596
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   REGION          152..203
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   711 AA;  80423 MW;  2153B45234011839 CRC64;
     MKIAAPSESQ SHCKKQDDKP NLVILKSLPR LDFEEVKTPR SLLEVRLATG VVVRTEKRIV
     RVRFSYQEKE FVDELIVLEL DDKFDMVLGM PWLARHDPVI DWTKRTIVRF GSSSSATESD
     GPVGAAHAPH AGLHDEAMRD QAGLERVRPR VKPAGEYKEQ LSTAGPGQEE TRGAGLRTRS
     ERRKREKLRK SRSGTETLQA VSAGQTQELE TTVETLNVLT RTSIGLQYKK MRLNNPPTLA
     SELMSLPVTS WKRFARELHD GRIEQICILS DVEMITCEAE ELNQLISEGA DALSAKSKKE
     RFDEQGWDSL KASPFFKVLR EYKDVLPDDI PAELPQDKGV QHEIDLVPGT KYCVTRQWPL
     PREQVKAIDD FFESRRNAGQ VRESKSPHSA PTFCVKKPQG GWRIVHAYNK LNDATVPAQT
     PIPRKDVIID SMTSSTVFST LDLRDGFYQI LMRESDISLT AVSTPSGMLW EWLVMPQGLK
     NAPATFNRCV THLLRSVRDF APSYFDDVFI HSRAVNGKSD VEMHAEHLRK LLELMRKHKL
     YANLKKCIFG ATQIPVLGCL VGKNGVRPDP GKVRVINEWP TPSNVKELRQ FLGLATYLCK
     YVSNYAGNIR PLSQLLKKEA AWEWTADCQQ AFEAVKQGLT EAPILAVAYQ DRPFHVVCDA
     SDFAIGCALM QLDHEGRDRV VYYQSRQLKP AERNYPTIRG LHRPRIVAYG D
//