ID H3GN35_PHYRM Unreviewed; 528 AA.
AC H3GN35;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=glucose-6-phosphate 1-epimerase {ECO:0000256|ARBA:ARBA00012083};
DE EC=5.1.3.15 {ECO:0000256|ARBA:ARBA00012083};
OS Phytophthora ramorum (Sudden oak death agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=164328 {ECO:0000313|EnsemblProtists:Phyra77983, ECO:0000313|Proteomes:UP000005238};
RN [1] {ECO:0000313|Proteomes:UP000005238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pr102 {ECO:0000313|Proteomes:UP000005238};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
RN [2] {ECO:0000313|EnsemblProtists:Phyra77983}
RP IDENTIFICATION.
RC STRAIN=Pr102 {ECO:0000313|EnsemblProtists:Phyra77983};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate;
CC Xref=Rhea:RHEA:16249, ChEBI:CHEBI:58225, ChEBI:CHEBI:58247;
CC EC=5.1.3.15; Evidence={ECO:0000256|ARBA:ARBA00001096};
CC -!- SIMILARITY: Belongs to the glucose-6-phosphate 1-epimerase family.
CC {ECO:0000256|ARBA:ARBA00005866}.
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DR EMBL; DS566025; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3GN35; -.
DR STRING; 164328.H3GN35; -.
DR EnsemblProtists; Phyra77983; Phyra77983; Phyra77983.
DR VEuPathDB; FungiDB:PSURA_77983; -.
DR eggNOG; KOG1594; Eukaryota.
DR eggNOG; KOG3374; Eukaryota.
DR HOGENOM; CLU_560784_0_0_1; -.
DR InParanoid; H3GN35; -.
DR Proteomes; UP000005238; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0047938; F:glucose-6-phosphate 1-epimerase activity; IBA:GO_Central.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd09020; D-hex-6-P-epi_like; 1.
DR Gene3D; 2.70.98.10; -; 1.
DR InterPro; IPR008183; Aldose_1/G6P_1-epimerase.
DR InterPro; IPR025532; G6P_1-epimerase.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR012349; Split_barrel_FMN-bd.
DR PANTHER; PTHR11122; APOSPORY-ASSOCIATED PROTEIN C-RELATED; 1.
DR PANTHER; PTHR11122:SF13; GLUCOSE-6-PHOSPHATE 1-EPIMERASE; 1.
DR Pfam; PF01263; Aldose_epim; 1.
DR Pfam; PF13883; Pyrid_oxidase_2; 1.
DR SUPFAM; SSF50475; FMN-binding split barrel; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005238};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..528
FT /note="glucose-6-phosphate 1-epimerase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003586392"
SQ SEQUENCE 528 AA; 57042 MW; E2172E97363248BC CRC64;
MPVSKSFVLN AACVVASCVA VASAELPTVK LTHPSGSNAE VFLFGAHVKS FHAAQDPTRD
VIFMSNHSYL DGVNPIMGGI PVVFPNFGSA TGLPGHGFAR VTNWTLAGVT EAADAASSTV
ATFTMAASDS TRKMWPVEFE LEYEVKISAE TLETALHVHN TNADEIAFHA LLHNYIYVDD
VRNGNTNVTG LAGLEYLDKV AKENKTESRP ELSIAAETDS VYYNAPSPLV VSSKGVNAAD
RVVTIDKSGI VGNGAHQKTV ATDAVIWNPW VERSKTFKDF GAEEYINMLA VEPGRVSEKQ
TLPAGQTYTL HQTITVTENL PLPLLLVLLV ASAIGGEIYS AATTSLVPEP TTDEADSGPI
AMLHAKHARM LVHENVWGVM ATTSVSFLGT AYANVVSYSD GVGFAKEDST GTMFFYLSVE
DLTAVDLKAK ANATMALSKA QGGPNACFMD PEDPTCWRLS LTGKVVPVDK GQRSYAERVV
FSKHPQMKHW PKNHGFRLYV LEIEQLVFLD FYGAAKHIAV NDYYKVKL
//
