ID H3GTW4_PHYRM Unreviewed; 656 AA.
AC H3GTW4;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
OS Phytophthora ramorum (Sudden oak death agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=164328 {ECO:0000313|EnsemblProtists:Phyra80614, ECO:0000313|Proteomes:UP000005238};
RN [1] {ECO:0000313|Proteomes:UP000005238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pr102 {ECO:0000313|Proteomes:UP000005238};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
RN [2] {ECO:0000313|EnsemblProtists:Phyra80614}
RP IDENTIFICATION.
RC STRAIN=Pr102 {ECO:0000313|EnsemblProtists:Phyra80614};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; DS566047; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3GTW4; -.
DR STRING; 164328.H3GTW4; -.
DR EnsemblProtists; Phyra80614; Phyra80614; Phyra80614.
DR VEuPathDB; FungiDB:PSURA_80614; -.
DR eggNOG; KOG0027; Eukaryota.
DR eggNOG; KOG1843; Eukaryota.
DR HOGENOM; CLU_030152_0_0_1; -.
DR InParanoid; H3GTW4; -.
DR OMA; LHGSTIM; -.
DR Proteomes; UP000005238; Unassembled WGS sequence.
DR GO; GO:0032587; C:ruffle membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0035091; F:phosphatidylinositol binding; IBA:GO_Central.
DR GO; GO:1900027; P:regulation of ruffle assembly; IBA:GO_Central.
DR CDD; cd00051; EFh; 1.
DR CDD; cd11526; SYLF_FYVE; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR007461; Ysc84_actin-binding.
DR PANTHER; PTHR15629:SF2; SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR15629; SH3YL1 PROTEIN; 1.
DR Pfam; PF00036; EF-hand_1; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF04366; Ysc84; 1.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 3.
DR PROSITE; PS50222; EF_HAND_2; 3.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000005238}.
FT DOMAIN 514..549
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 550..585
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 626..656
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 217..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..244
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..343
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 656 AA; 70914 MW; D18171001C661EC4 CRC64;
MPLHMPYHST MDKEVVKAAA ILDSCFKSTV DADSAIPAEM IQNASGLAFL TVIKAGMIWT
GKMGTGVVVA RLEDGSWSPP SGIGTAGLGF GAEIGGEIID FLIVLGSPSA VKTFKKGTQV
SVGAGLDLAV GPVGRTAGAS VNAGGGGVSG NYTYSHAKGA FAGVGLHGST FMVRGEMNSQ
FYGRKVTPNE ILSGQVAPPP GTCDVLFDSI RRACGQQGLG VEPNPNSFGS GRTSNSNSYH
SNGTPDAADH AAAARASFSG TRTSSISNSF SDSNRQLRTS SSTSSSLPAP TTTQADPNDP
RLRRYSSYKS ERELYAQFEQ RKSGVAPPVP TESTHSHPTN PSLKYKSYPA PAPNSAYTAP
PQAQAMYNSF VQPSAPKAPQ QSVPSLPSSV KGAEMKQVYS EVMNFVQTKC PYANLQVFKD
NCRLFGQDAM SLDAFFSYLL SICSHPQMKE LVPQLVRLLP TQEKRERLWL NELAGKKTQR
RFSTAKSRQR KQSEDVLYCA MIPSLRDQLH LKFTQIDACR ESFVHFDKDG SGTIDKYELS
KVLEAMGQKP TDEELFQMIA EVDNDHSGEI EFAEFLQVIE AQKLRAAQFD DESDFIDAFV
ACGGSADKTG HVERKMLVQL IKKDFGLPID IDRMLDELDT DGSGEIEYEE FKALLS
//
