ID   H3H438_PHYRM            Unreviewed;       497 AA.
AC   H3H438;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   13-SEP-2023, entry version 40.
DE   RecName: Full=Nucleotide-diphospho-sugar transferase {ECO:0008006|Google:ProtNLM};
OS   Phytophthora ramorum (Sudden oak death agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=164328 {ECO:0000313|EnsemblProtists:Phyra85315, ECO:0000313|Proteomes:UP000005238};
RN   [1] {ECO:0000313|Proteomes:UP000005238}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pr102 {ECO:0000313|Proteomes:UP000005238};
RX   PubMed=16946064; DOI=10.1126/science.1128796;
RA   Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA   Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA   Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA   Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA   Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA   McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA   Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA   Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA   Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA   Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT   "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT   of pathogenesis.";
RL   Science 313:1261-1266(2006).
RN   [2] {ECO:0000313|EnsemblProtists:Phyra85315}
RP   IDENTIFICATION.
RC   STRAIN=Pr102 {ECO:0000313|EnsemblProtists:Phyra85315};
RG   EnsemblProtists;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MNN1/MNT family.
CC       {ECO:0000256|ARBA:ARBA00009105}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS566160; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H3H438; -.
DR   EnsemblProtists; Phyra85315; Phyra85315; Phyra85315.
DR   VEuPathDB; FungiDB:PSURA_85315; -.
DR   eggNOG; ENOG502RBG3; Eukaryota.
DR   HOGENOM; CLU_030469_2_1_1; -.
DR   InParanoid; H3H438; -.
DR   OMA; IMCMHND; -.
DR   Proteomes; UP000005238; Unassembled WGS sequence.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000033; F:alpha-1,3-mannosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IBA:GO_Central.
DR   InterPro; IPR022751; Alpha_mannosyltransferase.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR31392; ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED; 1.
DR   PANTHER; PTHR31392:SF1; ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED; 1.
DR   Pfam; PF11051; Mannosyl_trans3; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005238};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        44..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..41
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          86..105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          421..440
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        86..104
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   497 AA;  56369 MW;  82F209DB7E5E2830 CRC64;
     MHDTSTLVSR GGGSSNDNSH VNAMESGRPT RSPSSSTAPS SSRTWTYVVS ILLVCIVMYS
     IMPPSVRQAP PKQLDVRAQQ VITDDRQATG MATHSPSSSQ RGAEFDTTVK RDKGVVMCMH
     NDAVPMGLSL VRELRCLGNQ ELVQVYHCFP EEMSDENRAL LLGADNRLEI VDVCSDLVKR
     KVLTQEVAEK FRNWWIKPLA MYHTDITEVL LLDIDDVFMH DPAVLRDTEG YKNTGTTFFY
     DRVLFSREFF NQNVNGTSYL RDMLNEFDYA KYGLDPEAHP SDHLKRSYAY RRQSSHEQDS
     SLVAINKALS GQAMPIMFWL ITEERFRREF SYGDKETFWI AFELAKQDYY FSPWGVGGIS
     SSTYDDLEKH SDTLCGSIVQ YMPELNKPAD FLYVNGKAML NPFPVVMEKL GTASHNVLFN
     TNPTHITPRQ RRKPNGRTRS GWKGGYAMEC LVGFGSEPLP AKFAPQLLRR RMFYFGIRMG
     VLSALDQCFP FEGMVEG
//