ID H3H6K2_PHYRM Unreviewed; 738 AA.
AC H3H6K2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 03-MAY-2023, entry version 47.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
OS Phytophthora ramorum (Sudden oak death agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=164328 {ECO:0000313|EnsemblProtists:Phyra86312, ECO:0000313|Proteomes:UP000005238};
RN [1] {ECO:0000313|Proteomes:UP000005238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pr102 {ECO:0000313|Proteomes:UP000005238};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
RN [2] {ECO:0000313|EnsemblProtists:Phyra86312}
RP IDENTIFICATION.
RC STRAIN=Pr102 {ECO:0000313|EnsemblProtists:Phyra86312};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; DS566603; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3H6K2; -.
DR EnsemblProtists; Phyra86312; Phyra86312; Phyra86312.
DR VEuPathDB; FungiDB:PSURA_86312; -.
DR HOGENOM; CLU_013497_0_0_1; -.
DR InParanoid; H3H6K2; -.
DR Proteomes; UP000005238; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00065; FYVE_like_SF; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR43102:SF2; GAF DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43102; SLR1143 PROTEIN; 1.
DR Pfam; PF01363; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005238};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 289..342
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 393..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..460
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 738 AA; 81732 MW; B2B37288CD94E5D2 CRC64;
MRWKRIGALA DENAKLYESA GRHNINSYSL RAVKPLQASL AEVEAVLTDH TALLGRDDTP
SLLARLLPAT YVSGGRIARY STLEHSTSER ENVALQYARL KPFTVTNQQQ ETKNSTLLES
VDNYVLLGYT LSTKLQRSDT SKKNKGTPRT SASVPSLLHL YRPVSAPTFA ERRHDFQTER
LATSDFSITY IIQEVASEEE QQKESTVTLE VVLTCSLDPK QDVEQDKEVL RQQKQRLRHD
ALCLTRLQPF IDAYRQEKTR GSVKEPQHDP KNCDPNMLRG SMFAGGRTCG VCHRKFGPFR
WKRHCETCEK VVCNQCLSVL AAAPSLSRRK KRVCSQCLYG ETANVAALHK AATGAVLDDG
KSSIDSAKVL ASPEKSATIS VFQFPSLETL VTKHKSSNAS SSEATPRVSG RVQIDLGLDP
SLASSVSKTP DRRRARSRQS QLSQGSVVSS TSNGSTASSF VAATPDIRRA TLSGRADFAD
VDESAMAKSM RTRRAKTVLL DDPHTKPAAH SHKSLNFITP LSSTAPTHSL YSTEGKQVEV
QQPQQEVVKP RASSYRGSKI QFVQLKTPEP DYELDYNWYN IFPKAPVDRS NAAEKARARY
VEVSGLKVDA RSLVFLRHDS ELEGLARCVL EVASQWHGCS INIVGSFEVY CLLTASNQRE
LDLDDELLEL EASPVTVDDV VPREESVSSY AVHHRSPFFV ADMEHDPRFR AHPLHTDQGV
VSLFSFPIYS SGADTSGS
//
