ID H3HAT4_PHYRM Unreviewed; 396 AA.
AC H3HAT4;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein {ECO:0000259|Pfam:PF02826};
OS Phytophthora ramorum (Sudden oak death agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=164328 {ECO:0000313|EnsemblProtists:Phyra93420, ECO:0000313|Proteomes:UP000005238};
RN [1] {ECO:0000313|Proteomes:UP000005238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pr102 {ECO:0000313|Proteomes:UP000005238};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
RN [2] {ECO:0000313|EnsemblProtists:Phyra93420}
RP IDENTIFICATION.
RC STRAIN=Pr102 {ECO:0000313|EnsemblProtists:Phyra93420};
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; DS565999; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3HAT4; -.
DR STRING; 164328.H3HAT4; -.
DR EnsemblProtists; Phyra93420; Phyra93420; Phyra93420.
DR VEuPathDB; FungiDB:PSURA_93420; -.
DR eggNOG; KOG0068; Eukaryota.
DR HOGENOM; CLU_019796_1_0_1; -.
DR InParanoid; H3HAT4; -.
DR OMA; WHHGTDK; -.
DR Proteomes; UP000005238; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR CDD; cd05300; 2-Hacid_dh_1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000005238}.
FT DOMAIN 181..361
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 396 AA; 43879 MW; 1DEFA9E2E0796658 CRC64;
MTAFTTSSNG DSVATASCMR VPIMTFIAGI GDNVRKEFAA SETPAGEFYR AGKLELVDIP
LPQLVGNKQD PLHGPSMVDP GRPIWDLTPE QQSVVEKAEI VLIDSHGGGP VFLDPKENLP
EDKQHILSNV KWVQATYAGV EMYLNLLPKG PNALTAEQLP KFTLTRAGGM MPRIMAQYVL
GYVTMIERKL LEAKEFQSKR DYARVEMISF RPAQSVTVGI LGLGDIGQYT GKMLRSCGYK
VLGFKRHVSA QDVAELAECA DHITTSLDDL LSKSDYLLNV LPSTNATRYL LNEDNLEKCR
ARSPVFINIG RGDVISEKTL IDALNKGTLS RAVLDVFEKE PLPNDSELWE HPSVLLTPHV
SGKVFPEDVA AMFLDNFNRY LKGEPVRYQV DWTKGY
//
