ID   H3K5I1_9FIRM            Unreviewed;       291 AA.
AC   H3K5I1;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   RecName: Full=HTH lysR-type domain-containing protein {ECO:0000259|PROSITE:PS50931};
GN   ORFNames=HMPREF9454_00504 {ECO:0000313|EMBL:EHR38699.1};
OS   Megamonas funiformis YIT 11815.
OC   Bacteria; Bacillota; Negativicutes; Selenomonadales; Selenomonadaceae;
OC   Megamonas.
OX   NCBI_TaxID=742816 {ECO:0000313|EMBL:EHR38699.1, ECO:0000313|Proteomes:UP000005963};
RN   [1] {ECO:0000313|EMBL:EHR38699.1, ECO:0000313|Proteomes:UP000005963}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIT 11815 {ECO:0000313|EMBL:EHR38699.1,
RC   ECO:0000313|Proteomes:UP000005963};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Morotomi M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Heiman D., Howarth C., Larimer J., Lui A.,
RA   MacDonald P.J.P., McCowen C., Montmayeur A., Murphy C., Neiman D.,
RA   Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P., Stolte C.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Megamonas funiformis YIT 11815.";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHR38699.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ADMB01000024; EHR38699.1; -; Genomic_DNA.
DR   RefSeq; WP_008537719.1; NZ_JH601090.1.
DR   AlphaFoldDB; H3K5I1; -.
DR   STRING; 437897.GCA_900128435_00006; -.
DR   GeneID; 69726952; -.
DR   PATRIC; fig|742816.3.peg.483; -.
DR   HOGENOM; CLU_039613_6_2_9; -.
DR   OrthoDB; 1624015at2; -.
DR   Proteomes; UP000005963; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd05466; PBP2_LTTR_substrate; 1.
DR   Gene3D; 3.40.190.290; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30419:SF8; HTH-TYPE TRANSCRIPTIONAL REGULATOR BSDA; 1.
DR   PANTHER; PTHR30419; HTH-TYPE TRANSCRIPTIONAL REGULATOR YBHD; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   291 AA;  32931 MW;  9324F1979F2A6BB9 CRC64;
     MELKQLEYFQ MTSRLKNITR AAKRLSVSQP NITVAIKKLE AELGIQLFER SQKQLSLTPE
     GAVFLNRIEL ALRNIQDAVL EVNDYKQLQK GTIKIGIPSM IGAYLFPKIF SGFQKKFAHL
     DIYLYEKGSM SIRESLERDE LDFGIVIISN ASPSLQLLPM STNQVVACVP EDSPLAQKDS
     LSWSDVSNID LIMLKEGSFI RNLIQQKLKE HNIQPNIILE SNQIETIKGL ISSNVGMAFL
     LDFVVQDTPH IKTLPIEDPI FVDVGLAWKK DRYISKAAQS FINFCQDTLN K
//