ID H3KFG9_9BURK Unreviewed; 1040 AA.
AC H3KFG9;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Efflux pump membrane transporter {ECO:0000256|RuleBase:RU364070};
GN ORFNames=HMPREF9440_01486 {ECO:0000313|EMBL:EHY31126.1};
OS Sutterella parvirubra YIT 11816.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sutterellaceae; Sutterella.
OX NCBI_TaxID=762967 {ECO:0000313|EMBL:EHY31126.1, ECO:0000313|Proteomes:UP000004956};
RN [1] {ECO:0000313|EMBL:EHY31126.1, ECO:0000313|Proteomes:UP000004956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIT 11816 {ECO:0000313|EMBL:EHY31126.1,
RC ECO:0000313|Proteomes:UP000004956};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU364070}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU364070}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. {ECO:0000256|ARBA:ARBA00010942,
CC ECO:0000256|RuleBase:RU364070}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHY31126.1}.
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DR EMBL; AFBQ01000218; EHY31126.1; -; Genomic_DNA.
DR RefSeq; WP_008542471.1; NZ_JH604974.1.
DR AlphaFoldDB; H3KFG9; -.
DR STRING; 762967.HMPREF9440_01486; -.
DR PATRIC; fig|762967.3.peg.1168; -.
DR HOGENOM; CLU_002755_0_1_4; -.
DR OrthoDB; 9176627at2; -.
DR Proteomes; UP000004956; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042908; P:xenobiotic transport; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004764; MdtF-like.
DR NCBIfam; TIGR00915; 2A0602; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF13; MULTIDRUG EFFLUX PUMP SUBUNIT ACRB-RELATED; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU364070};
KW Cell membrane {ECO:0000256|RuleBase:RU364070};
KW Membrane {ECO:0000256|RuleBase:RU364070};
KW Reference proteome {ECO:0000313|Proteomes:UP000004956};
KW Transmembrane {ECO:0000256|RuleBase:RU364070};
KW Transmembrane helix {ECO:0000256|RuleBase:RU364070};
KW Transport {ECO:0000256|RuleBase:RU364070}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 341..360
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 367..384
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 390..414
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 442..461
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 467..489
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 539..557
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 877..895
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 902..922
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 928..949
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 977..998
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
FT TRANSMEM 1004..1031
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364070"
SQ SEQUENCE 1040 AA; 112199 MW; EB9C63E89E7CC7CC CRC64;
MFSRFFIDRP VFAWVIAIVI MLAGTLSILN LPVSQYPMIA PPQVSISATY PGASAQTIEN
TVTQVIEQNL TGLDGYMYMN STSDSSGRVS ITVTFEAGTD PDMAQVQVQN KIQTAISTLP
QVVQQLGVTI QKTSASFLMV VGFISTDGRM NAADLSDFLV SNIQEPLSRV YGVGEAEVFG
ASYAMRVWLD PDKLVKYSLD TADVVSAIES QNVQISSGAL AAQPTDGRQE YTATIASSSL
LQTPEEFGEI LLKVTPEGSN VYLRDVAKIE IGQQTFMATG TYNGMPSSGM AIKLASGANA
LQTQESVLTR LEELKPNFPE GVEVVTPFDT TPFVRAALHE VVKTLFEAIV LVIVVMYLFL
QNWRATIIPT ITVPVVLLGT FAMLEASGFS INMLTMFAMV LAIGLLVDDA IVVVENVERV
MREDGSNAYD ATVKSMGQIQ GALVGIAMVL SAVFIPMAFF GGSTGVIYRQ FSVTIVSAMA
LSVLIALTLT PSLCAKYLLP VDHEEHHGKA GFFGWFNRGF DAFTHAVRDL IEHTINHKWV
TMACYVVVLG LMGLGFVKLP SAFMPAEDQG AMMLQMQLPQ GATMERTDRE LQRVENYVWK
TEENIVDSIF TVRGFSFAGT GQNMALGFVK LKDWSVRTDE ASGIDALQRR VMGPLMMSPE
FMNASTFLFP LPAVPELGVA DGFDFFIQDL SGQGHAKLME VRNAFLAEAA KDPRLTMVRH
NGMDDTAQMN LNIDRQKLSA LGLSIANVNS TISTALGGTY VNDFMDRGRI KQVWVQGQMD
SRMQPKDLER WHVKNATGEM VPLSSFMTTS WSYGSPRLER FNGLAAVNIQ GSPAAGVSSG
EAMAAVEEIA ARVFPHGYGI SWNGVSYQER EAGSNAAPLY GISLLVVFLC LAALYESWSI
PAAVILVVPC GVVGALGLTY ALGMNNDVYF QVGLLTTVGL VSKNAILIVE FAKDLMAEGA
DAVHAALEAV RLRLRPILMT SLAFGLGVLP LAMAHGAGSG AQNAIGVGVL GGMMTGTFLC
IAFVPVFYVL IAGIGRKKNA
//
