ID H3NRY5_9GAMM Unreviewed; 1058 AA.
AC H3NRY5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Cation/multidrug efflux pump {ECO:0000313|EMBL:EHQ56950.1};
GN ORFNames=OMB55_00006700 {ECO:0000313|EMBL:EHQ56950.1};
OS gamma proteobacterium HIMB55.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae.
OX NCBI_TaxID=745014 {ECO:0000313|EMBL:EHQ56950.1, ECO:0000313|Proteomes:UP000003408};
RN [1] {ECO:0000313|EMBL:EHQ56950.1, ECO:0000313|Proteomes:UP000003408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HIMB55 {ECO:0000313|EMBL:EHQ56950.1,
RC ECO:0000313|Proteomes:UP000003408};
RX PubMed=22493201; DOI=10.1128/JB.00171-12;
RA Huggett M.J., Rappe M.S.;
RT "Genome Sequence of Strain HIMB55, a Novel Marine Gammaproteobacterium of
RT the OM60/NOR5 Clade.";
RL J. Bacteriol. 194:2393-2394(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHQ56950.1}.
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DR EMBL; AGIF02000001; EHQ56950.1; -; Genomic_DNA.
DR AlphaFoldDB; H3NRY5; -.
DR STRING; 745014.OMB55_00006700; -.
DR PATRIC; fig|745014.4.peg.678; -.
DR eggNOG; COG0841; Bacteria.
DR OrthoDB; 5287122at2; -.
DR Proteomes; UP000003408; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF33; RND SUPERFAMILY EFFLUX PUMP PERMEASE COMPONENT; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003408};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..553
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 874..897
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 904..924
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 930..955
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 976..996
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1008..1034
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1058 AA; 114863 MW; 2EE1E306296F30DB CRC64;
MPKLIAWFVD NPVAANLLMF ILIASGLLAL NDVRKEEFPN IEAPVVMVTV PYLGAAPAEV
ETGVCTRIEE SIDGVENIVK VKTTAAEGQC NVAVELEMDA DKAKALDDIK AQVNAISTFP
ANTERPIVSQ VTMRSLVTQL AVHGKTDERS LKNITESIRK DLLELPEVSL VETLYMRADE
ISVEVSEATL RRHQLTLDQV AQAIRSSSID IPGGSVKADA GEIRLRGTGQ RYTGQELENV
VVAREPGGSR LLLRDIATIV DGFEDVDQYG EFNGEQAMMI QIFRIGSDDA IEISEAVLAY
AERKERELPE GIHFTIWNNE ADELVGRLGT MINNAFGGLL LVIISLSLFL RVRLALWVSA
GIPVAIFGAI AFFPSADLSI STLSLMGLLL SLGVVVDDAI VVGERIYTKE QAGLDPRSAA
IEGTSEVAVP VFFGVLTTIA AFMPLLNVDT NLGQFFYSIG GTVVLCLIFS IVESQLILPS
HLAHRSNTRR QSGFGKRWEV FQDRIAGSLE HFATHRYKGW IEWGIDNRYT TLAAALAMMV
IMAGFMASGR VVFQFFPAVS GNNVVARVVM PEGYPLAGTQ AVVQKLQASA AETRRRVDAS
RDDGSSAFKN ELSSVGVPIA QGAIVMLGAT GSHMAEVSLN LVPYRERGGM TPQEVVNLWR
DLTPPIPDVV ELSFSADAVS MGADIDLELR GRDIEQLGRA ANELTDILGG YGGLFDISNS
YRSGKRELAL KVLPEAEALG LTQADLGNQV RNAFYGQEAQ RVQRDRDDVR VMVRFPNDDR
RTLASLETMT IRLPDGTEVP ALSVAELTPT LGNSTINRTD GQRTLNVIAS ADRDAVAPET
ILSELFRTHV PQVMDDYPGV TVSQAGEAEE RTRALSGLVS ASLVALMVIY TLLAIPLKSY
LQPLVVMASI PFGFIGAILG HQIMSYDLVF FSLLGMIALA GVVINSSLVL VDFINRNRRI
HGMDLREAVV DSGMSRFRPI FLTSVTTFMG LLPLMVTRDF DTAPFVPLAV SLGFGVVFST
AVTLVLIPAL YVILEDFLSV FRDDVQEASA SEDASLAS
//
