ID H3NWL1_9GAMM Unreviewed; 263 AA.
AC H3NWL1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Enoyl-CoA hydratase domain-containing protein 3, mitochondrial {ECO:0000256|ARBA:ARBA00040545};
GN ORFNames=OMB55_00002540 {ECO:0000313|EMBL:EHQ56543.1};
OS gamma proteobacterium HIMB55.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae.
OX NCBI_TaxID=745014 {ECO:0000313|EMBL:EHQ56543.1, ECO:0000313|Proteomes:UP000003408};
RN [1] {ECO:0000313|EMBL:EHQ56543.1, ECO:0000313|Proteomes:UP000003408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HIMB55 {ECO:0000313|EMBL:EHQ56543.1,
RC ECO:0000313|Proteomes:UP000003408};
RX PubMed=22493201; DOI=10.1128/JB.00171-12;
RA Huggett M.J., Rappe M.S.;
RT "Genome Sequence of Strain HIMB55, a Novel Marine Gammaproteobacterium of
RT the OM60/NOR5 Clade.";
RL J. Bacteriol. 194:2393-2394(2012).
CC -!- FUNCTION: May play a role in fatty acid biosynthesis and insulin
CC sensitivity. {ECO:0000256|ARBA:ARBA00037410}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254, ECO:0000256|RuleBase:RU003707}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHQ56543.1}.
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DR EMBL; AGIF02000001; EHQ56543.1; -; Genomic_DNA.
DR AlphaFoldDB; H3NWL1; -.
DR STRING; 745014.OMB55_00002540; -.
DR PATRIC; fig|745014.4.peg.251; -.
DR eggNOG; COG1024; Bacteria.
DR OrthoDB; 9807606at2; -.
DR Proteomes; UP000003408; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR PANTHER; PTHR43602; -; 1.
DR PANTHER; PTHR43602:SF1; ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE 3: Inferred from homology;
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000003408};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
SQ SEQUENCE 263 AA; 28964 MW; 691E6DE087F729B9 CRC64;
MTAELILKDL NNGVLWLTLN NEKQRNPLSS QMLSTMTSVL DEAYDDDAVR CIVISAKGPV
FSAGHDLSEM ARGEDETKDE WRPRVLSVLE ACATMMQRIV HGPKAVVACV QGTATAAGCQ
LVSACDMAVA SSDSKFCTPG VNLGAFCTTP LVGIGRNLSR KHALEMALTG EFFDARDAER
FGLINRHVPA EEVVAETRRL AERIATRSPQ SIRDGKTAFY TQIEMPLHEA FEHANQVMVE
AMTSDESRRG VKAFFEKRAP DWR
//
