ID H3ZMW1_THELN Unreviewed; 654 AA.
AC H3ZMW1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Glyceraldehyde-3-phosphate:ferredoxin oxidoreductase {ECO:0000313|EMBL:EHR78758.1};
GN ORFNames=OCC_05826 {ECO:0000313|EMBL:EHR78758.1};
OS Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=523849 {ECO:0000313|EMBL:EHR78758.1, ECO:0000313|Proteomes:UP000015502};
RN [1] {ECO:0000313|EMBL:EHR78758.1, ECO:0000313|Proteomes:UP000015502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51850 / DSM 5473 / JCM 8560 / NS-C
RC {ECO:0000313|Proteomes:UP000015502};
RX PubMed=22493191; DOI=10.1128/JB.00123-12;
RA Gardner A.F., Kumar S., Perler F.B.;
RT "Genome sequence of the model hyperthermophilic archaeon Thermococcus
RT litoralis NS-C.";
RL J. Bacteriol. 194:2375-2376(2012).
CC -!- COFACTOR:
CC Name=W-bis(molybdopterin guanine dinucleotide); Xref=ChEBI:CHEBI:60537;
CC Evidence={ECO:0000256|ARBA:ARBA00001930};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the AOR/FOR family.
CC {ECO:0000256|ARBA:ARBA00011032}.
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DR EMBL; CP006670; EHR78758.1; -; Genomic_DNA.
DR RefSeq; WP_004068031.1; NC_022084.1.
DR AlphaFoldDB; H3ZMW1; -.
DR STRING; 523849.OCC_05826; -.
DR PaxDb; 523849-OCC_05826; -.
DR GeneID; 16549921; -.
DR KEGG; tlt:OCC_05826; -.
DR HOGENOM; CLU_440510_0_0_2; -.
DR OrthoDB; 84495at2157; -.
DR Proteomes; UP000015502; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016625; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor; IEA:InterPro.
DR Gene3D; 1.10.569.10; Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 2; 1.
DR Gene3D; 3.60.9.10; Aldehyde ferredoxin oxidoreductase, N-terminal domain; 1.
DR InterPro; IPR013984; Ald_Fedxn_OxRdtase_dom2.
DR InterPro; IPR013983; Ald_Fedxn_OxRdtase_N.
DR InterPro; IPR036503; Ald_Fedxn_OxRdtase_N_sf.
DR InterPro; IPR001203; OxRdtase_Ald_Fedxn_C.
DR InterPro; IPR036021; Tungsten_al_ferr_oxy-like_C.
DR NCBIfam; NF040818; GAPOR_Arch; 1.
DR PANTHER; PTHR30038; ALDEHYDE FERREDOXIN OXIDOREDUCTASE; 1.
DR PANTHER; PTHR30038:SF7; TUNGSTEN-CONTAINING GLYCERALDEHYDE-3-PHOSPHATE:FERREDOXIN OXIDOREDUCTASE; 1.
DR Pfam; PF01314; AFOR_C; 1.
DR Pfam; PF02730; AFOR_N; 1.
DR SMART; SM00790; AFOR_N; 1.
DR SUPFAM; SSF48310; Aldehyde ferredoxin oxidoreductase, C-terminal domains; 1.
DR SUPFAM; SSF56228; Aldehyde ferredoxin oxidoreductase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Tungsten {ECO:0000256|ARBA:ARBA00023245}.
FT DOMAIN 1..229
FT /note="Aldehyde ferredoxin oxidoreductase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00790"
SQ SEQUENCE 654 AA; 74473 MW; 25A45E8654C03193 CRC64;
MRFSVLKINL DEKKVESEEV EREGIYGIID YALYLHDEVY KTHELKDPYD PRNVMVFGKG
PFAGSVLPGA HRMTFVYRSP QYGGVFPSTM GGAAYQFQRV GVDFVVLEGK REKPTVIVLS
NDGENLNVEL HEIELEKVIE IWKDYKGEEG VYALTQYLID NFHEKFDGME YRIACVGPAS
LNTHMGAVFS QTLRNGKRVV GSEDWAARGG TGSVLLRAHN VVAIIFGGKA RKRFPKEDIS
NIRVAKPIVE GIHKKPMNEV ISEKTVKYRY NPKLKTGGTF GGNYPAEGDF VPILNWQMPY
IPKEERIKIH ENIMKYYWEP FNKEAIEPKN WTNCGEPCPV VCKKYANGHH IEYEPREANG
PLSGVITLRA SDISVHAVDA MGFDAISFGG TAAWVLELVY RGLLKPEEVG ISDKPEFGKD
SLLLKPVETS EKNAKLVAEL AHRVAFAETE IAKIIGEGIR RASEVLDEKF KDRLSYGESF
KDYGVYTPIG INGEIVPTMY WAIGNYIPLP IQGRYWTFYQ FGVFLEPEEL ANKIVASALY
EYWYDNVGWC RFHRGWAKPV LKALFMEAYG ENVDMEEQAK KTIRKLVNFL KKAGYEPVFW
DSMRVIDLVA KGAEEFGNER WAEQFKKDKV VTAKEYLRRV LAEYSRILGV DWTL
//
