ID H4GIZ5_9LACO Unreviewed; 285 AA.
AC H4GIZ5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN ORFNames=PS3_20224 {ECO:0000313|EMBL:EHS87107.1};
OS Limosilactobacillus gastricus PS3.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Limosilactobacillus.
OX NCBI_TaxID=1144300 {ECO:0000313|EMBL:EHS87107.1, ECO:0000313|Proteomes:UP000004567};
RN [1] {ECO:0000313|EMBL:EHS87107.1, ECO:0000313|Proteomes:UP000004567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PS3 {ECO:0000313|EMBL:EHS87107.1,
RC ECO:0000313|Proteomes:UP000004567};
RX PubMed=23846278;
RA Martin V., Cardenas N., Jimenez E., Maldonado A., Rodriguez J.M.,
RA Fernandez L.;
RT "Genome Sequence of Lactobacillus gastricus PS3, a Strain Isolated from
RT Human Milk.";
RL Genome Announc. 1:E00489-E00413(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHS87107.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AICN01000026; EHS87107.1; -; Genomic_DNA.
DR RefSeq; WP_007122028.1; NZ_AICN01000026.1.
DR AlphaFoldDB; H4GIZ5; -.
DR STRING; 1144300.PS3_20224; -.
DR PATRIC; fig|1144300.3.peg.599; -.
DR OrthoDB; 9802424at2; -.
DR Proteomes; UP000004567; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd07208; Pat_hypo_Ecoli_yjju_like; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR045943; DUF6363.
DR InterPro; IPR002641; PNPLA_dom.
DR InterPro; IPR037483; YjjU-like.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR PANTHER; PTHR14226:SF25; PHOSPHOESTERASE-RELATED; 1.
DR Pfam; PF19890; DUF6363; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000004567}.
FT DOMAIN 7..172
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
SQ SEQUENCE 285 AA; 31912 MW; 4326AEBEBA376791 CRC64;
MLYNAALVLE GGAMRGQYSA GVTDAFLKHH LEFKTVIGVS AGALCGANFV SKQYGRMVHV
NTHYRHDPNY ISSLNIIKKQ PVVNLDFLFD DHGWDWNNFD EEAYQRSATD FTIVATSLAG
KTVSFTNPLG EKLVEALKAS SSMPFLFDPQ PTDQGLCLDG GVTDSIPFDL AQAKGFDKIV
VVRTRPRDYQ KKATSPLLKR LYQRHYRDYP DFITAAINRP EVYNQQVATL NQLEDKGQIY
VIAPENPVKV GRLESNVKKI QALYDEGQAQ AEALISEIEE YLAKN
//
