ID   H4GJB7_9LACO            Unreviewed;       289 AA.
AC   H4GJB7;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Transcription regulator {ECO:0000313|EMBL:EHS87007.1};
GN   ORFNames=PS3_18761 {ECO:0000313|EMBL:EHS87007.1};
OS   Limosilactobacillus gastricus PS3.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Limosilactobacillus.
OX   NCBI_TaxID=1144300 {ECO:0000313|EMBL:EHS87007.1, ECO:0000313|Proteomes:UP000004567};
RN   [1] {ECO:0000313|EMBL:EHS87007.1, ECO:0000313|Proteomes:UP000004567}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PS3 {ECO:0000313|EMBL:EHS87007.1,
RC   ECO:0000313|Proteomes:UP000004567};
RX   PubMed=23846278;
RA   Martin V., Cardenas N., Jimenez E., Maldonado A., Rodriguez J.M.,
RA   Fernandez L.;
RT   "Genome Sequence of Lactobacillus gastricus PS3, a Strain Isolated from
RT   Human Milk.";
RL   Genome Announc. 1:E00489-E00413(2013).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHS87007.1}.
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DR   EMBL; AICN01000032; EHS87007.1; -; Genomic_DNA.
DR   RefSeq; WP_007122150.1; NZ_AICN01000032.1.
DR   AlphaFoldDB; H4GJB7; -.
DR   STRING; 1144300.PS3_18761; -.
DR   PATRIC; fig|1144300.3.peg.814; -.
DR   Proteomes; UP000004567; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 3.40.190.290; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30346:SF0; HCA OPERON TRANSCRIPTIONAL ACTIVATOR HCAR; 1.
DR   PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000004567}.
FT   DOMAIN          2..59
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   289 AA;  32357 MW;  3D741F03E190DCDD CRC64;
     MIDYQLLEEL VTFQETGTLS ATAEKLLITQ PSVTRGMQKL EDELGVSLFD RTVNRLKLNS
     TGELAAKLAR KALAANQDFV TITQNYARQQ NAITIASIAP GPLLLLNYLQ TQNDELTNIV
     LKPVMSVTDV KESLLSAESQ LAFITDPLDS DHIIEEPIGV EQLYLSISTF HALASYPKVT
     FDDLADMSFI LSDDIGIWHD IIQNAIPNLH PLVQNSEEAI QQLTSFSDFP AFNSNITQLT
     SNRNTDNRKS VLIDDDRARM KFFAAYVNEQ ADRVKPIIEL MKALWPTKK
//