ID H4GK66_9LACO Unreviewed; 327 AA.
AC H4GK66;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:EHS85627.1};
GN ORFNames=PS3_8349 {ECO:0000313|EMBL:EHS85627.1};
OS Limosilactobacillus gastricus PS3.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Limosilactobacillus.
OX NCBI_TaxID=1144300 {ECO:0000313|EMBL:EHS85627.1, ECO:0000313|Proteomes:UP000004567};
RN [1] {ECO:0000313|EMBL:EHS85627.1, ECO:0000313|Proteomes:UP000004567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PS3 {ECO:0000313|EMBL:EHS85627.1,
RC ECO:0000313|Proteomes:UP000004567};
RX PubMed=23846278;
RA Martin V., Cardenas N., Jimenez E., Maldonado A., Rodriguez J.M.,
RA Fernandez L.;
RT "Genome Sequence of Lactobacillus gastricus PS3, a Strain Isolated from
RT Human Milk.";
RL Genome Announc. 1:E00489-E00413(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHS85627.1}.
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DR EMBL; AICN01000061; EHS85627.1; -; Genomic_DNA.
DR RefSeq; WP_007122449.1; NZ_AICN01000061.1.
DR AlphaFoldDB; H4GK66; -.
DR STRING; 1144300.PS3_8349; -.
DR PATRIC; fig|1144300.3.peg.1312; -.
DR Proteomes; UP000004567; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06291; PBP1_Qymf-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF95; RIBOSE OPERON REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000004567};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..59
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 327 AA; 36855 MW; 5C26113EB2D654A9 CRC64;
MNQRVKLDDV AEKAGVSKTT VSRVLNHRGY LSDQTIKKVH QAMEELHYRP NVVARHLYHQ
KTNQVGLVFP TVNDPFFAHL ESRLAYELYE RGYATLMGNS QNNPDKERRF LHYLLDGQID
GLIVGAHNQG LSEYQETNLP IVSIERWVAP KIPIVASDNY AGGLMATQRL LDDGCQNIIH
TNYPRLESST NQRRQQAYED LMIQHHRQPI TYEVNFDSPV EDKVAIFKKI FAEHPEVDGI
VADNDTNASL IIHLAQELGY QVPDQLKVVG FDGADTTQIL MPELTTIKQP INDLASTAVD
LLIKRINGEE NVASVILPVT LHEGTTA
//
