ID   H5U497_9ACTN            Unreviewed;       818 AA.
AC   H5U497;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Putative dimethylglycine oxidase {ECO:0000313|EMBL:GAB40555.1};
GN   ORFNames=GOSPT_109_00080 {ECO:0000313|EMBL:GAB40555.1};
OS   Gordonia sputi NBRC 100414.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC   Gordonia.
OX   NCBI_TaxID=1089453 {ECO:0000313|EMBL:GAB40555.1, ECO:0000313|Proteomes:UP000005845};
RN   [1] {ECO:0000313|EMBL:GAB40555.1, ECO:0000313|Proteomes:UP000005845}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 100414 {ECO:0000313|EMBL:GAB40555.1,
RC   ECO:0000313|Proteomes:UP000005845};
RA   Yoshida I., Hosoyama A., Tsuchikane K., Katsumata H., Yamazaki S.,
RA   Fujita N.;
RT   "Whole genome shotgun sequence of Gordonia sputi NBRC 100414.";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAB40555.1}.
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DR   EMBL; BAFC01000107; GAB40555.1; -; Genomic_DNA.
DR   RefSeq; WP_005207627.1; NZ_BAFC01000107.1.
DR   AlphaFoldDB; H5U497; -.
DR   eggNOG; COG0404; Bacteria.
DR   eggNOG; COG0665; Bacteria.
DR   Proteomes; UP000005845; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   PANTHER; PTHR13847:SF181; TRANSFERASE CAF17, MITOCHONDRIAL-RELATED; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
FT   DOMAIN          5..372
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          375..430
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          432..710
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          733..810
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   818 AA;  88995 MW;  DF8B06AB19068AA1 CRC64;
     MPTPKVVIVG AGIVGTSLAD ELTARGWTDV TVLDRGPLFA TGGSTSHAPG LVFATNPSKT
     MTELASYTLE KFSTLEHPDG WCFSHLGGLE VATTEARLDD LHRKAGWAAS RGVEHELLSP
     AECLERHPLL DPDQIVGGFF TPRDGLAKAL RAAEAQATRA ISRGARFVPH TEVIDVVECN
     GEVRGVRTAT GVVDADIVVC CTGFWGREFG RRVGLTIPLV PMAHQYAYTT PLESRHGANS
     VVAEASLPIL RHQDHDLYYR EHGDRLGIGY YGHRPMPSDV NALDYDSTVS LEEMPSKLMF
     TPDDFAEAWD QTITLIPELA TGKVDDGFNG IFSFTPDGHS VVGEHRGLKG FWVAEAVWVT
     HSAGIARTVA EWMVDGAPSV DTHEFDLYRF ENAALTDDYI LTTSSQSFVE VYDIIHPHDQ
     VAAPRGVRTS PFYDRQAALG AEFWVANLWE RPAWFEANQP ILDELVAGGL QIPLRDAWSA
     RNWSPISVAE AAWTRSHVAM YDMTPLTRYE VSGPGAADFL QRMTTNNVDK SIGSITYTLM
     LDDEGGVRSD LTVARLGADL FQVGANGPID FDWLSRHLPA DRSVTLRDIT GATCCIGLWG
     PSARDVVAPL TPTGLTNDGL KYFRCVQTTI GSVPVTLMRV SYVGELGWEI YADAEYGRGL
     WDLLMAAGAE HRIIAAGRIA FNALRIEKGY RSAGVDMTTE HTPDAAGLSF AVKSSKPEFV
     GKNALDQRVC PLRLRTLKFD DPAAVVLGKE PVRVDGDVVG YVTSAGWSPT VGACLAYAWL
     PSDLPDSTAV AVDYLRTSYG ALVISDPVVD PEMARIKQ
//