ID H5UP98_9MICO Unreviewed; 587 AA.
AC H5UP98;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Putative signal peptide peptidase {ECO:0000313|EMBL:GAB47556.1};
GN ORFNames=MOPEL_020_00420 {ECO:0000313|EMBL:GAB47556.1};
OS Mobilicoccus pelagius NBRC 104925.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermatophilaceae;
OC Mobilicoccus.
OX NCBI_TaxID=1089455 {ECO:0000313|EMBL:GAB47556.1, ECO:0000313|Proteomes:UP000004367};
RN [1] {ECO:0000313|EMBL:GAB47556.1, ECO:0000313|Proteomes:UP000004367}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 104925 {ECO:0000313|EMBL:GAB47556.1,
RC ECO:0000313|Proteomes:UP000004367};
RA Yoshida Y., Hosoyama A., Tsuchikane K., Katsumata H., Yamazaki S.,
RA Fujita N.;
RT "Whole genome shotgun sequence of Mobilicoccus pelagius NBRC 104925.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S49 family.
CC {ECO:0000256|ARBA:ARBA00008683}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAB47556.1}.
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DR EMBL; BAFE01000019; GAB47556.1; -; Genomic_DNA.
DR RefSeq; WP_009481454.1; NZ_BAFE01000019.1.
DR AlphaFoldDB; H5UP98; -.
DR STRING; 1089455.MOPEL_020_00420; -.
DR eggNOG; COG0616; Bacteria.
DR OrthoDB; 9764363at2; -.
DR Proteomes; UP000004367; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR CDD; cd07018; S49_SppA_67K_type; 1.
DR CDD; cd07023; S49_Sppa_N_C; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR004634; Pept_S49_pIV.
DR InterPro; IPR004635; Pept_S49_SppA.
DR InterPro; IPR002142; Peptidase_S49.
DR InterPro; IPR047217; S49_SppA_67K_type_N.
DR InterPro; IPR047272; S49_SppA_C.
DR NCBIfam; TIGR00706; SppA_dom; 1.
DR PANTHER; PTHR33209; PROTEASE 4; 1.
DR PANTHER; PTHR33209:SF1; SERINE PROTEASE SPPA, CHLOROPLASTIC; 1.
DR Pfam; PF01343; Peptidase_S49; 2.
DR PIRSF; PIRSF001217; Protease_4_SppA; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000004367};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825}.
FT DOMAIN 104..259
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT DOMAIN 359..509
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT ACT_SITE 176
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
FT ACT_SITE 375
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
SQ SEQUENCE 587 AA; 62360 MW; 5DDA88DCED1901A6 CRC64;
MSGFSDLLDR LPFDTRGLRK LPVPGISGSC LLELDLARGI GETSPTSPVE ALRERHTPTL
HAVVEGLRDA TGDDKVLGLI VHAYAPALAP AHAEEVRAAV EGFSDSGKPV VAWAETYGEM
TNGVAGYLVA TAADEIWLQP SGYLQINGAA VQAVFLREAL DKIDVEPQFD KRREYKSAVE
TFTQRDISEP NREMLTSLTE SALEVLLTGI ARGRGLDVDD VRAVLDEGAL TPVRAGELRL
VDRIGYRDEA YTALRTRVGA EPDVELRYVE RYDLGFSAVE AVRGRGRKTV AIVQANGAIH
LGRSGNAPLG GRSIGSDSLG AALRQVADDD KIGAVVLRVD SPGGSAVASD AIRREILRLR
EEKPVVASMG TVAGSGGYFI SMPATEIVAD GTTLTGSIGV YAGKFVTQGG LDRLGIHRTQ
IERGRYAGML SDQRPFTEDE WALLSRMLDE IYADFTTKAA EDRGMPVEQL EPLARGRVWT
GAQAADLGLV DHVGGMRAAI DRACALADLD PETTPTRISP KLGVLDRFLP ADNSDAVTRT
TTGLGGAAVR GTVTAALGEG VPLLDQALAA LGARGAGVLT MTPTRWT
//
