ID H5UQS1_9MICO Unreviewed; 652 AA.
AC H5UQS1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Acetoacetyl-CoA synthetase {ECO:0000313|EMBL:GAB48079.1};
GN Name=acsA {ECO:0000313|EMBL:GAB48079.1};
GN ORFNames=MOPEL_041_00230 {ECO:0000313|EMBL:GAB48079.1};
OS Mobilicoccus pelagius NBRC 104925.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermatophilaceae;
OC Mobilicoccus.
OX NCBI_TaxID=1089455 {ECO:0000313|EMBL:GAB48079.1, ECO:0000313|Proteomes:UP000004367};
RN [1] {ECO:0000313|EMBL:GAB48079.1, ECO:0000313|Proteomes:UP000004367}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 104925 {ECO:0000313|EMBL:GAB48079.1,
RC ECO:0000313|Proteomes:UP000004367};
RA Yoshida Y., Hosoyama A., Tsuchikane K., Katsumata H., Yamazaki S.,
RA Fujita N.;
RT "Whole genome shotgun sequence of Mobilicoccus pelagius NBRC 104925.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAB48079.1}.
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DR EMBL; BAFE01000037; GAB48079.1; -; Genomic_DNA.
DR AlphaFoldDB; H5UQS1; -.
DR STRING; 1089455.MOPEL_041_00230; -.
DR eggNOG; COG0365; Bacteria.
DR Proteomes; UP000004367; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000004367}.
FT DOMAIN 28..81
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 91..467
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 534..608
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 652 AA; 70159 MW; 3340F0BECCA2825F CRC64;
MSWQIENPRL ARFAADAERR WARPLPDYPA LHAWSVQHPE EFWASVWDDF GVVTSAPYEA
VLTGGPMPHH EWFPGARLNY ADQIFRHDTR DGAAVVSYEE DGTRTELSWS ELEKQVRAVA
GTLRGLGVGE GDRVVGYLTN GPETIVAFLA TASLGAIWAV CAPDLGAATA ASRLAQLEPS
VLVANTAYDW AGCTYDRRAE VVDLAAATGV TALVEVPRSG LTFDGDDAPA LGAGAPRVTW
AEALTGAPVE ATAQVPANHP LWVLFSSGTT GVPKGMVHSH AGVVAAHASM FLLAMDCGPD
DTLFWYTTPN WMMWNIVVSA LLVGSRTVTY EGNVAYPGPD RLWRIVADER VTMFGTSPGQ
LQLSAQTRLE PGRDLDLSAL RAVPVTGAPA PAALNQWLRE HVRADVPLLS VCGGTDVVSA
FLGCSPWLPV YDGELSGPAL GVDAQAWDAD GNPVTDEVGE LVIASPGPSM PLYFWNDPDG
SRYKASYFDT YPGAWRQGDW VTRTGRGSFV VHGRSDSTLN RNGVRFGSSD IYDIVESDPA
VAEAVVLGVE LDGGGYRMPL FLAPAPGHEL DEAELDRIRG RLRTEGSPRH VPDEIHVVRA
VPHTRTGKKL EIPLKRILQG ADPFAVLDPG AIDDASLVDD YVALARTWGT RG
//
