ID   H5V2P9_ATLHE            Unreviewed;       395 AA.
AC   H5V2P9;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE            EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE   AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN   Name=entC {ECO:0000313|EMBL:GAB52335.1};
GN   ORFNames=EH105704_06_01070 {ECO:0000313|EMBL:GAB52335.1};
OS   Atlantibacter hermannii NBRC 105704.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Atlantibacter.
OX   NCBI_TaxID=1115512 {ECO:0000313|EMBL:GAB52335.1, ECO:0000313|Proteomes:UP000010297};
RN   [1] {ECO:0000313|EMBL:GAB52335.1, ECO:0000313|Proteomes:UP000010297}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 105704 {ECO:0000313|EMBL:GAB52335.1,
RC   ECO:0000313|Proteomes:UP000010297};
RA   Yoshida I., Hosoyama A., Tsuchikane K., Katsumata H., Yamazaki S.,
RA   Fujita N.;
RT   "Whole genome shotgun sequence of Escherichia hermannii NBRC 105704.";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC         ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00000799};
CC   -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC       {ECO:0000256|ARBA:ARBA00005297}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAB52335.1}.
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DR   EMBL; BAFF01000006; GAB52335.1; -; Genomic_DNA.
DR   RefSeq; WP_002436125.1; NZ_BAFF01000006.1.
DR   AlphaFoldDB; H5V2P9; -.
DR   eggNOG; COG1169; Bacteria.
DR   Proteomes; UP000010297; Unassembled WGS sequence.
DR   GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR015890; Chorismate_C.
DR   InterPro; IPR004561; IsoChor_synthase.
DR   NCBIfam; TIGR00543; isochor_syn; 1.
DR   PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   SUPFAM; SSF56322; ADC synthase; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010297}.
FT   DOMAIN          125..380
FT                   /note="Chorismate-utilising enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00425"
SQ   SEQUENCE   395 AA;  43280 MW;  4B47C8A6D152E102 CRC64;
     MEASLAEETQ QRAVTLSPDS FFFMSPHRNL ATSGCLTRLT APAADGEDLN GEFQQRLRET
     FAAARKLGCS RPIVVGAIPF DTRKPSALFV PREYQSFSHS EMLASARTAA PPQLQLTAQQ
     AIPEKTQFLD MVERAAALTA TPDVRKVVLS RLIDISTASA PDRHQLLNRL VALNPGSYNF
     HVPLADGGAL IGASPELLLR KENQHFWSLP LAGSARRHPN QTEDKLVGDR LLNSTKDRHE
     HQLVTQAMRQ ILAGRSQRLE VPEIPSLITT PTLWHLATAI AGETRSEQEN ALSLACLLHP
     TPALSGFPHT VARQVIAELE PFDRELFGGI VGWCDDRGNG EWAVAIRCAR LKDNQIRCFA
     GAGIVPASVA ESEWHETGVK LSTMLNVFGL NDRSV
//