ID H5WM72_9BURK Unreviewed; 503 AA.
AC H5WM72;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=BurJ1DRAFT_3701 {ECO:0000313|EMBL:EHR72506.1};
OS Burkholderiales bacterium JOSHI_001.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX NCBI_TaxID=864051 {ECO:0000313|EMBL:EHR72506.1, ECO:0000313|Proteomes:UP000004674};
RN [1] {ECO:0000313|EMBL:EHR72506.1, ECO:0000313|Proteomes:UP000004674}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JOSHI_001 {ECO:0000313|EMBL:EHR72506.1,
RC ECO:0000313|Proteomes:UP000004674};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Zeytun A., Lu M., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Smith J., Lewis G.,
RA Woyke T.;
RT "Noncontiguous Finished sequence of Burkholderiales bacterium JOSHI_001.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM001438; EHR72506.1; -; Genomic_DNA.
DR AlphaFoldDB; H5WM72; -.
DR STRING; 864051.BurJ1DRAFT_3701; -.
DR eggNOG; COG3706; Bacteria.
DR HOGENOM; CLU_541501_0_0_4; -.
DR OrthoDB; 9813903at2; -.
DR BioCyc; BBAC864051:G1H30-3688-MONOMER; -.
DR Proteomes; UP000004674; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004674};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 185..230
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 363..498
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT COILED 298..335
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 503 AA; 54590 MW; AB21016BFBC480D5 CRC64;
MPRIPMLSPT WRVAFGLVGL VASLLLLVDF LFGVLPDREA EARRVRTIVA ESVTTQTTEF
LRKQETARIG TLLEAVRNRT PDLRSAAVRE KGGRLLVASG AHAPDWAQQA DDVSSGHRVV
VPIHSAQGQW GRMEFDFEPV TAVGGAGWLH ERRLWLAVGL PLAGLLLIYL YLRRTLMQLN
PMTVVPERLR DAFDALTEGV ALLDLNGRVV LANEALRRMA GVGDEGIHGR PFASGARLTM
EPTDEPPWAQ VLRGGAIVRG TRVQVGSGSQ KRSGVLNCSP IADPDGRVRG CLATIGDVTE
IEHSNHELRL ALANLEQSRM QIEAQNQELV RLATRDALTG LHNRRAFFDS AGGLLANHAS
RGTGFAVLML DVDHFKSFND QHGHATGDQV LQSVARQIAD TLRQQDVVAR YGGEEFCALL
SNVDELQAHA LAERVREAVA DNAGRGLRAG DDLRVTISVG LCATTAGSAE LSELLKRADD
ALYQAKRGGR NRVVTHCAET TAV
//
