ID H5X0X4_9PSEU Unreviewed; 638 AA.
AC H5X0X4;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Succinate dehydrogenase/fumarate reductase flavoprotein subunit {ECO:0000313|EMBL:EHR51974.1};
GN ORFNames=SacmaDRAFT_3761 {ECO:0000313|EMBL:EHR51974.1};
OS Saccharomonospora marina XMU15.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharomonospora.
OX NCBI_TaxID=882083 {ECO:0000313|EMBL:EHR51974.1, ECO:0000313|Proteomes:UP000004926};
RN [1] {ECO:0000313|EMBL:EHR51974.1, ECO:0000313|Proteomes:UP000004926}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XMU15 {ECO:0000313|EMBL:EHR51974.1,
RC ECO:0000313|Proteomes:UP000004926};
RX PubMed=22768369; DOI=10.4056/sigs.2655905;
RA Klenk H.P., Lu M., Lucas S., Lapidus A., Copeland A., Pitluck S.,
RA Goodwin L.A., Han C., Tapia R., Brambilla E.M., Potter G., Land M.,
RA Ivanova N., Rohde M., Goker M., Detter J.C., Li W.J., Kyrpides N.C.,
RA Woyke T.;
RT "Genome sequence of the ocean sediment bacterium Saccharomonospora marina
RT type strain (XMU15(T)).";
RL Stand. Genomic Sci. 6:265-275(2012).
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DR EMBL; CM001439; EHR51974.1; -; Genomic_DNA.
DR RefSeq; WP_009155355.1; NZ_CM001439.1.
DR AlphaFoldDB; H5X0X4; -.
DR STRING; 882083.SacmaDRAFT_3761; -.
DR eggNOG; COG1053; Bacteria.
DR HOGENOM; CLU_014312_8_1_11; -.
DR OrthoDB; 9805351at2; -.
DR Proteomes; UP000004926; Chromosome.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF89; SUCCINATE DEHYDROGENASE [IRON-SULFUR SUBUNIT] (SUCCINIC DEHYDROGENASE)-RELATED; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PIRSF; PIRSF000171; SDHA_APRA_LASPO; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000004926}.
FT DOMAIN 10..429
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 488..607
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 322
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000171-1"
SQ SEQUENCE 638 AA; 70197 MW; D8471F7A4728B3BD CRC64;
MTEVERHSYD VVVIGAGGAG LRAVIEARQR GLSVAVVCKS LFGKAHTVMA EGGCAASMGN
ANPNDNWQVH FRDTMRGGKF LNNWRMAELH AKEAPDRVWE LETYGALFDR TKDGRISQRN
FGGHTYPRLA HVGDRTGLEL IRTMQQKIVS LQQEDNKKYG DYEAKLKVFA ECTVTELLKQ
DGRIAGAFGY WRESGRFILF ETPAVVLATG GIGKSFKVTS NSWEYTGDGH ALALRAGADL
INMEFVQFHP TGMVWPPSVK GILVTEGVRG DGGVLKNSEG ERFMFRYIPD VFKGQYADSE
AEADRWYEDA DNNRRTPDLL PRDEVARAIN AEVKAGRGSP HGGVFLDIAS RLPAEEIRRR
LPSMYHQFKE LADVDITKEP MEVGPTCHYV MGGIEVDPDS AAASVPGLFA AGECSGGMHG
SNRLGGNSLS DLLVFGRRAG LGAADYVESL SGRPEVADSD VDTAAKRAVA PFDPPGQAVA
EENPYTLHTE LQQCMNDLVG IIRKADEMEQ ALGKLADIRR RIAGVTVEGH RQYNPGWHLA
LDLRNMLLVS ECVAQAALRR GESRGGHTRD DHPQMDAKWR NTLLVCGAAD GDPSIPDVTV
RAKEQQPMRQ DLLGLFELSE LEKYYTSEEL ANHPERKA
//
