ID H5XB16_9PSEU Unreviewed; 727 AA.
AC H5XB16;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Anaerobic dehydrogenase, typically selenocysteine-containing {ECO:0000313|EMBL:EHR53746.1};
GN ORFNames=SacmaDRAFT_5630 {ECO:0000313|EMBL:EHR53746.1};
OS Saccharomonospora marina XMU15.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharomonospora.
OX NCBI_TaxID=882083 {ECO:0000313|EMBL:EHR53746.1, ECO:0000313|Proteomes:UP000004926};
RN [1] {ECO:0000313|EMBL:EHR53746.1, ECO:0000313|Proteomes:UP000004926}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XMU15 {ECO:0000313|EMBL:EHR53746.1,
RC ECO:0000313|Proteomes:UP000004926};
RX PubMed=22768369; DOI=10.4056/sigs.2655905;
RA Klenk H.P., Lu M., Lucas S., Lapidus A., Copeland A., Pitluck S.,
RA Goodwin L.A., Han C., Tapia R., Brambilla E.M., Potter G., Land M.,
RA Ivanova N., Rohde M., Goker M., Detter J.C., Li W.J., Kyrpides N.C.,
RA Woyke T.;
RT "Genome sequence of the ocean sediment bacterium Saccharomonospora marina
RT type strain (XMU15(T)).";
RL Stand. Genomic Sci. 6:265-275(2012).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CM001439; EHR53746.1; -; Genomic_DNA.
DR AlphaFoldDB; H5XB16; -.
DR STRING; 882083.SacmaDRAFT_5630; -.
DR eggNOG; COG0243; Bacteria.
DR HOGENOM; CLU_000422_13_3_11; -.
DR Proteomes; UP000004926; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR PANTHER; PTHR43105:SF14; POSSIBLE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000004926}.
FT DOMAIN 11..67
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 727 AA; 77739 MW; 7E68920423CA88FF CRC64;
MWPLVYHDGV MATAHITCPL CEATCGLSVT VENGTVTDVR GDAEDVFSHG YICPKGASLG
ALHHDPDRLR APLVKRAGRF TEVSWDEAFA EIDARLPALL NDHGRDAVAV YAGNPSVHNV
SSALYSRALF KAIGTRNVYT ASTVDQMPKH FSCGYLFGDP FSIPVPDLDR TRHLLILGAN
PLVSNGSLMT AADVRGRLRA IQRRGGKIVV VDPCRTRTAR LADEHHRIRP GTDAALLFAL
VQVIFTENLV RLGRLEEHVN GLERLAELAA PFTPEVVAPL SGIDAGAIRE LARELARADR
AAVYGRIGTT AQPFGTLTSW LIDVLNVLTG NLDSEGGAMF PLAAAGQVNS SGGRSKPFTA
GRWRSRVRGY PEVFGELPVA ALAEEITTPG DGQIRALLTV AGNPCLSGPN AAKLSEALAE
LDFMVSVDVY VNETTRHADV ILPGPSPLMR PHYDVALYQL AVRNVANWTP PALPSDQPQE
WQTLLRLTGI VTGQGPDADI EALDELVAAD TARRAGLDPT VAGERNGPQR LLDLMLRAGP
YELTLADLEA APHGVDLGPL RPRLPDILCT ASKKIELAAE PIVSDVGRLV AELGEKPDDR
LVLIGRRQLH SNNSWMHNLP PLVRGSNRCT AQVHPDDAQR LGLTEGGTAT FTTRTGKVSA
TVELTDDVRP GVVSIPHGWG HDVEGLRTAV ATAHAGVNSN LLSDDRLLDV LSGTAALNGI
PVDVTPG
//
