ID   H5XTC8_9FIRM            Unreviewed;       331 AA.
AC   H5XTC8;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Putative Zn-dependent hydrolase of beta-lactamase fold {ECO:0000313|EMBL:EHQ88387.1};
GN   ORFNames=DesyoDRAFT_1219 {ECO:0000313|EMBL:EHQ88387.1};
OS   Desulfosporosinus youngiae DSM 17734.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC   Desulfosporosinus.
OX   NCBI_TaxID=768710 {ECO:0000313|EMBL:EHQ88387.1, ECO:0000313|Proteomes:UP000005104};
RN   [1] {ECO:0000313|EMBL:EHQ88387.1, ECO:0000313|Proteomes:UP000005104}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17734 {ECO:0000313|EMBL:EHQ88387.1,
RC   ECO:0000313|Proteomes:UP000005104};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Ovchinnikova G., Lu M., Land M.L., Hauser L., Pester M.,
RA   Spring S., Ollivier B., Rattei T., Klenk H.-P., Wagner M., Loy A.,
RA   Woyke T.J.;
RT   "The Noncontiguous Finished genome of Desulfosporosinus youngiae DSM
RT   17734.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CM001441; EHQ88387.1; -; Genomic_DNA.
DR   AlphaFoldDB; H5XTC8; -.
DR   STRING; 768710.DesyoDRAFT_1219; -.
DR   eggNOG; COG2220; Bacteria.
DR   HOGENOM; CLU_020884_1_2_9; -.
DR   OrthoDB; 9805728at2; -.
DR   Proteomes; UP000005104; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   PANTHER; PTHR15032:SF36; LACTAMASE_B DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR15032; N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D; 1.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EHQ88387.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005104};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        25..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          93..290
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|Pfam:PF12706"
SQ   SEQUENCE   331 AA;  36517 MW;  7802BEC4DF5383B1 CRC64;
     MKNQINLISS ESLNPTPKRL SRRKFIGLGL LGTLGLTGGY SVIDNVFGKQ SENKTGQKLV
     KPNFIPTPNK WSNDDVTVSW LGHASFLINF FGTRILIDPA LNSHIGITPI GNLTIGPSRY
     IASALSSDEV GPIDLVLVSH AHTDHFDYPT LRKLQSPNTS VVTAKNTLPL WDGMKFKSIN
     EIHWQDSKSL AGVNVTAIEG QHWGARIPWK KGMEANSLLL SKNGIHIFFG ADTGYTELIK
     QQLSGIPIDL AIMGIGAYSP KSFEAKHATP EQAWKMAEEI SAKWVIPMHW GAFNLSREPM
     KEPIIRFRQA ASGQMEKVAI QETGGTWILP R
//