ID H5XUD3_9FIRM Unreviewed; 215 AA.
AC H5XUD3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family {ECO:0000313|EMBL:EHQ89369.1};
GN ORFNames=DesyoDRAFT_2286 {ECO:0000313|EMBL:EHQ89369.1};
OS Desulfosporosinus youngiae DSM 17734.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfosporosinus.
OX NCBI_TaxID=768710 {ECO:0000313|EMBL:EHQ89369.1, ECO:0000313|Proteomes:UP000005104};
RN [1] {ECO:0000313|EMBL:EHQ89369.1, ECO:0000313|Proteomes:UP000005104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17734 {ECO:0000313|EMBL:EHQ89369.1,
RC ECO:0000313|Proteomes:UP000005104};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Lu M., Land M.L., Hauser L., Pester M.,
RA Spring S., Ollivier B., Rattei T., Klenk H.-P., Wagner M., Loy A.,
RA Woyke T.J.;
RT "The Noncontiguous Finished genome of Desulfosporosinus youngiae DSM
RT 17734.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM001441; EHQ89369.1; -; Genomic_DNA.
DR RefSeq; WP_007783008.1; NZ_CM001441.1.
DR AlphaFoldDB; H5XUD3; -.
DR STRING; 768710.DesyoDRAFT_2286; -.
DR eggNOG; COG0110; Bacteria.
DR HOGENOM; CLU_081811_2_0_9; -.
DR Proteomes; UP000005104; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd03360; LbH_AT_putative; 1.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR020019; AcTrfase_PglD-like.
DR InterPro; IPR041561; PglD_N.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR NCBIfam; TIGR03570; NeuD_NnaD; 1.
DR PANTHER; PTHR43300; ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR43300:SF7; UDP-N-ACETYLBACILLOSAMINE N-ACETYLTRANSFERASE; 1.
DR Pfam; PF17836; PglD_N; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:EHQ89369.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005104};
KW Transferase {ECO:0000313|EMBL:EHQ89369.1}.
FT DOMAIN 3..82
FT /note="PglD N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17836"
FT ACT_SITE 138
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
FT BINDING 71
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT BINDING 147
FT /ligand="acetyl-CoA"
FT /ligand_id="ChEBI:CHEBI:57288"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT SITE 139
FT /note="Increases basicity of active site His"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
SQ SEQUENCE 215 AA; 22259 MW; EEA5785F2718806B CRC64;
MGKLLILGAG GHGKVVAECA LSLGIYTTIA FLDDDEKVIE ESILGSCPVI GTFSDAGSFV
HKFSEAFVAL GNNRSRVRLI TYLREIGYKI PCLIHPAAYV SKSAHIEIGT VIMAGAVVNA
DAHIGVGGII NTGASVDHDC VLGVGVHLSP GARLGGTVTV GDYTWICMGA NVVNNVHVGK
GSVAAAGATV IRDVGDNLLV AKVPARELKK TDLKR
//
