ID H6BNH6_EXODN Unreviewed; 730 AA.
AC H6BNH6;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Chromatin assembly factor 1 subunit B {ECO:0000313|EMBL:EHY52353.1};
GN ORFNames=HMPREF1120_00567 {ECO:0000313|EMBL:EHY52353.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY52353.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY52353.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY52353.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JH226130; EHY52353.1; -; Genomic_DNA.
DR RefSeq; XP_009152814.1; XM_009154566.1.
DR AlphaFoldDB; H6BNH6; -.
DR STRING; 858893.H6BNH6; -.
DR GeneID; 20305206; -.
DR VEuPathDB; FungiDB:HMPREF1120_00567; -.
DR eggNOG; KOG1009; Eukaryota.
DR HOGENOM; CLU_010127_3_1_1; -.
DR InParanoid; H6BNH6; -.
DR OMA; CIVSNLH; -.
DR OrthoDB; 5478541at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006335; P:DNA replication-dependent chromatin assembly; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR045145; PTHR15271.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15271; CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; 1.
DR PANTHER; PTHR15271:SF4; CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 10..52
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 59..90
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 71..172
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 118..159
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 160..194
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 203..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 567..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..256
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..588
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 591..608
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..692
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..709
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 77334 MW; 2C94D062304A72F5 CRC64;
MKAAPLLISW HNESAPIYSV HFDPHGKGRL ATAGNDNNVR LWSIEAQGEE RKVTYLSTLT
RHTQPVNVVR FCPKGEMLAS AGDDGNVLLW VPSESSMATL TEEHADDKET WRIKHMCRTS
SGAEIYDLAW SPDGQYFITG GVDNTARIFS AHTGTMIRQI AEHNHFVQGV AWDPLNEFIA
TQSSDRSVHI YALKLKDGTP TLSTHGKFNK MDLPGRRISS HSPAPPPDLP HRASNASANN
LAIVSPAPSN PGTPLTTALP MDPPMLTASR RSSFGSSPSF RRSASPAPTL PLPAVRPEIS
SPSLNAAMGL AVKNTNIYHN ETMTSFFRRL TFSPDGSLLF TPAGHYKTAF PTTGDPTKTA
EDVSNTVYIY TRAGFNKPPV AHLPGHKKPS VAVKCSPVLY TLRSTSKPTN HITIDTSSAS
EEIPLLPDPI VPQSTSTSKQ PASLSTATSA PESMAAPSPK PAVENESANS APPPAFSLPY
RIIYAVATQD AVFVYDTQQT TPLCVVSNLH YAAFTDLTWS NDGLTLLMSS TDGYCSTLAF
TPGELGQVYT GPRPTYNHPI VSTSIPLPTA SSNSTPIPTP TAAASPSLTK ASPVPAPPSI
PSPAPFIIRP GSPARSNSQS SIATMASIQT SGLASNATPT MGHVPLVTAA NSGPLVGIPP
MTTPPQTPAS IQGGQHSATS SISGTILGKR DVGTTSESEK EEGKSKRRRI APTLVAPAGS
AEVPKTDEKS
//
