ID H6BRC5_EXODN Unreviewed; 1904 AA.
AC H6BRC5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Adenosinetriphosphatase {ECO:0000313|EMBL:EHY54706.1};
GN ORFNames=HMPREF1120_02871 {ECO:0000313|EMBL:EHY54706.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY54706.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY54706.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY54706.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JH226131; EHY54706.1; -; Genomic_DNA.
DR RefSeq; XP_009155167.1; XM_009156919.1.
DR STRING; 858893.H6BRC5; -.
DR GeneID; 20307510; -.
DR VEuPathDB; FungiDB:HMPREF1120_02871; -.
DR eggNOG; KOG0392; Eukaryota.
DR HOGENOM; CLU_000315_1_1_1; -.
DR InParanoid; H6BRC5; -.
DR OMA; WYSDIAC; -.
DR OrthoDB; 180798at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR CDD; cd17999; DEXHc_Mot1; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR044972; Mot1.
DR InterPro; IPR044078; Mot1_ATP-bd.
DR InterPro; IPR022707; Mot1_central_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR36498; TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172; 1.
DR PANTHER; PTHR36498:SF1; TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172; 1.
DR Pfam; PF12054; DUF3535; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1330..1503
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1678..1826
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 184..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 240..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..725
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..744
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1904 AA; 211038 MW; 029A0F19E2A857F1 CRC64;
MAASRLDRLV TLLDKGSTQL IRNTAAAQLA DIQKQNPDNL FALLGRVLPY LQSKSWETRT
AAAKAIGGIV SNVPKFDPNA DEAEIKDEVP KSEDGELKVE VKTEDKVQEA DDLLQLATLD
IKMILRHGKK LLGSAGKEYE YSMAGMTPAQ RLHHQKQSLT ARLGLGGEYM EEDLVTENDF
AATSQHKLAQ TPGPPRVDTK SAGQRTDSIG APSPYSAMSP SENGQPFLEE SGLSKRQLNQ
LKRKNKSAAK VGASKMRVVD LSGRRPSEPG QTPVSATPHP VKLNGQDESN GDSKQDYFSI
KREGPDDNTA LISEFKGDVV EEKPLIQPDE EHSHDWPFEV MCDFLSIDLF DPNWEVRHGA
AMGLREVLRV HGRGAGRRYG RSRAENDLAN RRWLDDMACR LLCVLMLDRF GDYVSDTVVA
PIRESIGQTL GALLTQLPDD TAVSVYNFLQ QMINQSDTGL KQPIWEVCHG GMIGLRYFVA
VRKDLLLQHN ALIDGVVSAV IRGLAHPDDD VKSVSAATLV PVAGELTTIR PQSLGQLIGV
VWDCLLDMQD DLSASTGAVM DLLATLCSYD ATLEAMRKNA AEDPEQSFEM LVPRLYPFLR
HTITSVRLAV LKALVTFLNL SNVNNMEWVG GRVTRLLFQN MLLERNEGVL RMSFEVWEAL
VAFMERQGMA KFAPNLDPHI MPMLKATIQP VGQSRSPIPM DASLLIKPSG TPMATSAPRQ
GSASDADQQP KKRRKVDKAD KADANQQPSH NTDGHMLHGE VDLVGMEVIL RTRITCSRAL
GLLLGKQNEA AVASYWTSLL PIINSNHSSS RLFTGMILEE LARNQSIKPT DTASCVAQLQ
SVLDDDGHHW YSDIVSSLQA ARGQCQSLIS AFQNNAHVSR DKLPAIAVVC QGENGAGPKA
FSLADAEKIV TTDFDRLLKS LTPAQRVSGT QYLNDARTNA MTAVEEARKI KEGRDLAIKA
AVASVLVRLG EIPKKPGQLI KCIMDSIKGE EFEELQARSA SAVAALIDFY TRGAKKGPVD
KLVSNLVKFT CVDTSETPEF GPNAKFEDIV LSLRKEEDRK DHPDAAKFEQ EAKEARIMRR
GAKRALDELA QSYGGELLEK LPVLKSLIEN PIGELVEPAD PATLQVDEER GQSLIDAFSI
LRTLSPTLHP TLHPWILSLS PLIGKAMRSR LSVVRYSAAK CFATICSVIP IEGMTMLVQD
ILPNISNPLD LRDRQGITEC VYHLIWVMGD RILPYVIFLI VPVLGRMSDA NHDIRLLATT
SFATLVKLVP LEAGIPDPPG MPESLLQGRE RERKFMAQML DPKKVEPFQI PVAIKAELRS
YQQEGVNWLA FLNKYNLHGV LCDDMGLGKT LQTLCIVASD HHMRAEEYAK TKAPDMRRLP
SLIVCPPTLS GHWQQEIKQY APFLSCVAYV GNPMERNSRL HLLEQADVVI TSYDVCRNDN
DVLAPITWNY CVLDEGHLIK NPKAKITQAV KKLVSNHRLI LSGTPIQNNV LELWSLFDFL
MPGFLGTEKV FQDRFAKPIA ASRNAKSSSK EQEAGALAIE ALHKQVLPFL LRRLKEEVLN
DLPPKILQNY YCDLSDLQKR LFEDFFKKER KTVENSIGAA DKEAKQHIFQ ALQYMRKLCN
SPALVVKEGT KQYETISKQL AASKSSLRDV AHAPKLTALR DLLVDCGIGV SNDSNEMSAS
NYVSQHRALI FCQMKEMLDM VQNEVLAKLL PSVQFLRLDG SVEATKRQNI VNQFNNDPSY
DCLLLTTSVG GLGLNLTGAD TVIFVEHDWN PQKDIQAMDR AHRIGQKKVV NVYRLITRGT
LEEKIMSLQR FKIDVASTVV NQQNAGLGSM ETDQILDLFN LGEGTDTGGE SGGAGKEEDM
VDLETGEVKK KGEKGWLDDV GELWDERQYE EEFNLDSFVQ NLQK
//
