ID H6BT50_EXODN Unreviewed; 362 AA.
AC H6BT50;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=DNA-repair protein complementing XP-A cells {ECO:0000313|EMBL:EHY54300.1};
GN ORFNames=HMPREF1120_02470 {ECO:0000313|EMBL:EHY54300.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY54300.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY54300.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY54300.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH226131; EHY54300.1; -; Genomic_DNA.
DR RefSeq; XP_009154761.1; XM_009156513.1.
DR AlphaFoldDB; H6BT50; -.
DR STRING; 858893.H6BT50; -.
DR GeneID; 20307109; -.
DR VEuPathDB; FungiDB:HMPREF1120_02470; -.
DR eggNOG; KOG4017; Eukaryota.
DR HOGENOM; CLU_053731_0_1_1; -.
DR InParanoid; H6BT50; -.
DR OMA; HQWGRSV; -.
DR OrthoDB; 1344100at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd21077; DBD_Rad14; 1.
DR Gene3D; 3.90.530.10; XPA C-terminal domain; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000465; XPA.
DR InterPro; IPR022656; XPA_C.
DR InterPro; IPR037129; XPA_sf.
DR NCBIfam; TIGR00598; rad14; 1.
DR PANTHER; PTHR10142; DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS; 1.
DR PANTHER; PTHR10142:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS; 1.
DR Pfam; PF05181; XPA_C; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 209..259
FT /note="XPA C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05181"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 39..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 304..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 41455 MW; F1BDC083A86B97C9 CRC64;
MSQSRLTPPP RSDEAQARAS LTPEQVRRIE INRLKAKALR EQREAEAATE SRLRTPDASV
AGQKRRYGTF SGVPATIRDA RTDGDPGRPL EAIRPARNFT KYVDYDFSKM ADTKGGFLTA
DDDPHNKAMH ADEQDNKPAH MTQKEWERQQ LLKSLRNQKA GPFEPGISAV RDETTQSCRE
CGTLEVDWKW LDVFGLAVCN ACKEKYPEKY SLLTKTEARE DYLLTDPELK DEKLLPHLER
PNPHKSTWHN MFLYLRCQVE EYAFSEKRWG SPEALDAEFE RREEEKKRRK ENKFKSKLAD
LKKRTRVEAH QRSRKGGGGN FGDDLGDGKH VHEFGLPVDN PESGITLKKC VICGLEVEEL
DL
//
