ID H6BYP7_EXODN Unreviewed; 1604 AA.
AC H6BYP7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN ORFNames=HMPREF1120_04827 {ECO:0000313|EMBL:EHY56760.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY56760.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY56760.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY56760.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH226133; EHY56760.1; -; Genomic_DNA.
DR RefSeq; XP_009157221.1; XM_009158973.1.
DR STRING; 858893.H6BYP7; -.
DR GeneID; 20309466; -.
DR VEuPathDB; FungiDB:HMPREF1120_04827; -.
DR eggNOG; ENOG502QWE7; Eukaryota.
DR HOGENOM; CLU_001023_0_0_1; -.
DR InParanoid; H6BYP7; -.
DR OMA; LHHAHRM; -.
DR OrthoDB; 1368013at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0005938; C:cell cortex; IEA:InterPro.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0032065; P:maintenance of protein location in cell cortex; IEA:InterPro.
DR CDD; cd13365; PH_PLC_plant-like; 1.
DR InterPro; IPR024774; PH_dom-Mcp5-type.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR28190; NUCLEAR MIGRATION PROTEIN NUM1; 1.
DR PANTHER; PTHR28190:SF1; NUCLEAR MIGRATION PROTEIN NUM1; 1.
DR Pfam; PF12814; Mcp5_PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304}.
FT DOMAIN 1214..1325
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 140..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 355..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 526..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 937..1007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1045..1177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1357..1486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1579..1604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 64..132
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 204..305
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..546
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..730
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 969..1007
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1048..1084
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1151..1177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1364..1423
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1424..1438
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1439..1453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1462..1479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1604 AA; 173279 MW; F75D6F5183052C1B CRC64;
MATAAMAGSE NTPNNDMHAS VNDLSDPFVD EFQPRVSSHA HRYSSLVDPD SITLGTSASP
SQVKRSIIAH LAETERRLQD AQKLGQSLLL QQSQLTEKLH EVEAQQGDAE ISPELRQRLA
DLEKEHNDVG KEIARALLGP KSRAVSGEEK PASEQSTFSS QATASPTKVT APSRRQRNQP
SNRAGDLQFA ADISTSLLAQ VRQLQSAVAE RDELLKQVSA ERDQLEQDKS VFAQRLRVLD
ESEQKYKDEN WNLETQTHEL LAAAREAADR EKRLTASLSA AVAEKSRLQS EMDEIRLAHD
KLADEHASTR KAHDSELHTL KRTIELGDSE RAALQGKIDE LTAQNHELAR AVAARLRGPN
SDAEISANQE PEEEFRNYDD LENSPPASPT KATPRHGGLE SETLRSSLHH AHRMIQNLKN
NIHREKTEKI ELKRMLQEAR DELEQRRGDG SLGSGTKRQK TKSDIIKKPP RLDMLGGSRR
MQMDIELEDD DWEDHFADTP THNKHLTIPT AAEGRSADVS DAYQTANETE GAFETADERH
ATESEDFQTG AESLAGDSTD DLTETEETAS HGRRLGPIRA LRPSLAFKPA GDRQSFISTA
STSAGEDEDE LKTPIVAQSH KFRIRNGRDS FARQSRVPTD STPINLMSDA ISQDSPATVT
SERSTPAAEQ SLFAELGGMD DASSFGTPGR TSIASVSSTP GFPGYTPSQR TVSQATPLSA
PKTSMVDSGT MTEPWKPESD RPARVLIDAG TVMEPPSPDH DDLRTPLPSD FPLPPTVPVS
PIKQIDNGTQ YTPQRLQLQD SPMRNTAFIT PPKTVWDEAQ SPGVLPSETG STPHPQTPGQ
LNYSGLLMHD TAPKSPENVI TLPPHVSLRE PESLTFSIIQ TQSTEPIEAE PANKSTGVAA
STQVEDLPSR PTTAEKVSTT GLLASAAAAM GFAKSNEGSN PVIAEDETSE PVDAANGSQR
EKHQPLRDTS GNRMPTKTAF PAKSSNPNQE DRLPLASSND QSSQTLLTSE QIEEALRAKS
AVPVAFPEVK GTPDITARPL TPLAPAEASQ GSKLSETQAE PLQPMTSNPS PIKRPSNAYN
QWTAASMAPH PPLPPDHKAA IAKAGGRVAS PTRGESASNQ GPTIMGPPAL PASAMRRPKT
PADSIRSPTR ESDAPRTSNV SRGHRGTITS QLSHRSSVSS FASEIDERFN MQPNAHAGPH
GFGTDPRIIQ AITQTMIGEF LWKYTRKAGR AEMSETRHLR YFWVHPYTKT LYWSDKDPQT
AGRNELKAKS VLIQSVQVVP DDNPMPPGLH RKSLEVITPG RRVRFTATTG QRHETWFNAL
NYLLLRGDDV NSGTYTTGGD HVTGEDVDEF NVNAGGYGAT LAPTGSRMSL SSYNSRTTRG
TSSNRASAAQ RQPAAATAGI ANTSATRVVP QDSTASRTAP NSTVRRSRAE HSRQGSDQER
TVRASSVSRF SRMIGSVTGR GRRMSETANT HSHSMTGGRS EGGSIYDASV VSDGRVDSAE
ELRREMLRQE EIGFGGLENV RACCDGKHDV STLSHSHRNA TGHGHTHRAL SMSMSLRGTA
RRGGGGGGFT SAATTPARAN AAAGSVGPGA TPTRTGGATA ATAT
//
