ID H6C1N5_EXODN Unreviewed; 409 AA.
AC H6C1N5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:EHY57764.1};
GN ORFNames=HMPREF1120_05788 {ECO:0000313|EMBL:EHY57764.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY57764.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY57764.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY57764.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SDS22 family.
CC {ECO:0000256|ARBA:ARBA00023460}.
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DR EMBL; JH226134; EHY57764.1; -; Genomic_DNA.
DR RefSeq; XP_009158225.1; XM_009159977.1.
DR AlphaFoldDB; H6C1N5; -.
DR STRING; 858893.H6C1N5; -.
DR GeneID; 20310427; -.
DR VEuPathDB; FungiDB:HMPREF1120_05788; -.
DR eggNOG; KOG0531; Eukaryota.
DR HOGENOM; CLU_044236_0_0_1; -.
DR InParanoid; H6C1N5; -.
DR OMA; EVWASYN; -.
DR OrthoDB; 8274at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR003603; U2A'_phosphoprotein32A_C.
DR PANTHER; PTHR45973; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED; 1.
DR Pfam; PF12799; LRR_4; 2.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00365; LRR_SD22; 10.
DR SMART; SM00369; LRR_TYP; 6.
DR SMART; SM00446; LRRcap; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 8.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 385..403
FT /note="U2A'/phosphoprotein 32 family A C-terminal"
FT /evidence="ECO:0000259|SMART:SM00446"
FT REGION 1..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 409 AA; 46416 MW; 3EE9FC70AC06F0AD CRC64;
MADQDQEADN APLNNPPKDD EQQQQKNEEE QKVEPVQAQI EIHAHTHIEV SAPVATGGSH
STPLVNSSGW DGKLRMPPRN AVLTNPEALS DPEYSDPEAP PVEQIEADED LLDDYPLDTE
DVDLVHCRIS SLPALRLERF TKVKRLCLRQ NAIQSISLPA ELGETLQELD LYDNLISHIK
GLEDMKNLTS LDLSFNKIKH IKNVNHLQKL KELYFVQNRI SKIENLENLD NLTMIELGAN
RIREIENLEP LHNLRELWLG KNKITEIKGL NSLTNLRLLD IKSNRLTTIS GLDTLPNLEE
LYVSHNGITE ISATALANNP KLRVLDISNN QISHLANIGH LQDLEELWAS SNKLSDFREV
ERELADKEHL ETVYFEMNPL QLTAPAVYRN KIRLALPQVK QIDATYVRV
//
