ID H6C1Q7_EXODN Unreviewed; 600 AA.
AC H6C1Q7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=Arf-GAP domain-containing protein {ECO:0000259|PROSITE:PS50115};
GN ORFNames=HMPREF1120_05810 {ECO:0000313|EMBL:EHY57786.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY57786.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY57786.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY57786.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH226134; EHY57786.1; -; Genomic_DNA.
DR RefSeq; XP_009158247.1; XM_009159999.1.
DR AlphaFoldDB; H6C1Q7; -.
DR STRING; 858893.H6C1Q7; -.
DR GeneID; 20310449; -.
DR VEuPathDB; FungiDB:HMPREF1120_05810; -.
DR eggNOG; KOG0703; Eukaryota.
DR HOGENOM; CLU_023062_3_3_1; -.
DR InParanoid; H6C1Q7; -.
DR OMA; SDCKRNK; -.
DR OrthoDB; 1022106at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd08839; ArfGap_SMAP; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR044732; ArfGAP_SMAP1-like.
DR PANTHER; PTHR45705; FI20236P1; 1.
DR PANTHER; PTHR45705:SF1; FI20236P1; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 14..124
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 123..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 600 AA; 61964 MW; 7A649487AA36723F CRC64;
MSQRPPPERA AQNAQTLKAL VKLEGNKVCA DCKRNKHPRW ASWNLGVFIC IRCSGIHRGM
GTHISRVKSV DLDAWTDEQL QSILKWGNSR ANKYWEAKLA PGHVPSEAKI ENFIRTKYES
KRWVMDGPMP DPSTLDEHGD DDMPLNLVQE KAKIERSASQ SQRQTAAQPP PRPRQAAPAN
VDLFDDFAPT PPVRPSTTDI PTQRPTQTGP PAPAPAAAPK AASKPQDSLL GLDFFGNTPS
AGIGRPSSAA SNPTQSTNSR GDLKSSILSL YASAPKPQPA AQPQHNREPS FGGMTSPPAK
QDAFGGLADA FGGLNFSSGN ATAPAPAPAS SARPSSTFSA FSSLPSSVPS KATPAAPQIT
SPPPLSGGSF FDTVPSKPPA PKPNVTSPLP SNGLDFSFTQ KVTSPPPAPA AAPKPAPSSI
PADLFAAEEF GGFASSVPTS PPKPASPKVT SSASATAPIS SPFNLSAQPA PAPKPADQPF
KAPTIAPSSS ALFDPWGSGT DSSPWGAPEP APAKPAAPKV DLGRPPEHIT ANDISGGWAE
PISSASSKPA HQPTVTADED FGGWTSAAGP AAAAPPAAAA PKGTSNGFGA VPDVFDNPWG
//
