ID H6C3C7_EXODN Unreviewed; 2319 AA.
AC H6C3C7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=SNF2 N-terminal domain-containing protein {ECO:0000259|Pfam:PF00176};
GN ORFNames=HMPREF1120_06160 {ECO:0000313|EMBL:EHY58142.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY58142.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY58142.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY58142.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH226134; EHY58142.1; -; Genomic_DNA.
DR RefSeq; XP_009158603.1; XM_009160355.1.
DR STRING; 858893.H6C3C7; -.
DR GeneID; 20310799; -.
DR VEuPathDB; FungiDB:HMPREF1120_06160; -.
DR eggNOG; KOG0298; Eukaryota.
DR HOGENOM; CLU_000796_0_0_1; -.
DR InParanoid; H6C3C7; -.
DR OMA; SMIPYIT; -.
DR OrthoDB; 103295at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45626:SF26; FAMILY HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09120)-RELATED; 1.
DR PANTHER; PTHR45626; TRANSCRIPTION TERMINATION FACTOR 2-RELATED; 1.
DR Pfam; PF00145; DNA_methylase; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1348..1453
FT /note="SNF2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00176"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1589..1662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1834..1873
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1998..2034
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..64
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1589..1620
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2319 AA; 258866 MW; A7427E63FA8BC168 CRC64;
MARKKARVAS TGDQVTKPGT STPTQQQKSS SKTEEAPSSS KTAAPKEWKI SKGESKAWPS
QPDDWDREYF DDELKFVNPT KKAGCMTGIG VRFKDTGKNK ATARPREGRR VYQTLSNSSD
ASVMSTPNDT TKMTASAPES ECFQTLLGIC KALDNTKIQT LDELLRRKPV DQECLPLPEE
KSSTSKPRLS SDEDDYEDDE DDEITDLGTG YFSHQGLDLT APPLSDIDEI FGCLADTGKR
LGLLESIMPF ASKGARIFTM CSGTESPIIA LDLLRKALSL SGFDKFSYQH LGSAEIEPQK
QAFIERNFRP PVIFRDVTEF IPYADAKAKQ EDYKSIRPFS AYGRRADPPE GVHILIAGSS
CVDYSSLNSH KKQSDGESAQ TLWGIFAYAR AHQPNIIILE NVANALWDQL AGNLTNYGLS
YFVVPVKVNS INYYVPQTRI RGYCLLINIE HARRVGLDLE LAGMEFVRSM ARFQRRASSP
YKDFLLDEDD LRLKLAKENP GDFDTRERLV NWAACRKRHL DVRVSLQLGM SNPYTRRQNN
SQCKLEDHAW QHWALAQTER VRDTLDINYL RYVVERDFDM RTKHRNFNVS QNVDRDNDSR
QFGVVGCITP RGGLFHTARG GPLTGLEVFA LQGMPIGDLN LSKDSSRDLQ DLAGNAMTTT
VIGAAILSAL IACHKATKQQ PGTIEQTTIF QQYTDEHGGD DVTATEAGSL AQPLLSETEL
VARSKEFPLQ SDHDSFSIKD AIPLGDMIIR AKASQPLCRC EGIERHATEL LICLGCFFTT
CGSCSRDAHD GLQELQTESL GVSRQSARSF VQQLIRSLPP VLALQGQYTS ALDQLTSKGF
FLHHKSSIKK AFEENLYFQG VRFDGSWKAT YESGYATLQL SFVPVFTQPP PNTKRALPNV
SNALAKLSIQ PTWLLFVKPP STEPAESKLR DLLLHPVARM RPSRTLMSGE WELWKGLDKS
HKVNIFGTGT KQPSWEQNLG LKGAPFNTME VFSEIEVKPA LDANGEVPLA LQRIIGKYRL
LQQCPAASGT LHRKVSESQH DDSPVFMFLD PHPVREAFSD RVVFATQPPR GVSTDERYIL
ARLPAPWRPA VLTKWPEGQT LDCELVAQWS EAQGAGLELA VPAEGRQIRK WYQPAEFNVG
ANVQCRNSAS TLFVVQLRLN PDQQKRFPPG RVITIELENK PDVLRGFGWI ISHASDVPHL
NAGWQSVDDA QTAVCLACSP RAPELRWVMQ QVGKRDIVKP IENAEEAAVF EDALKRRPKP
TVALIHCHGD QAFLEIQLNV STLIHRANGK FASSSGSLTQ LLDSSWRLTR HDPFAARPVF
TSLQLRDNES EQPVSTTDIR QRKLWISQRK IIAWMQKQEQ NPPSWKELAL VESCLPAVGW
RLEARARLQV QVRGGIIADD VGAGKTTTAL GLVALDQLSS YSSFTTQPQD TYMDTHATLI
LMPKNIIKQW EAEGIECLGW KKFDPKKARN PQPYYLLIQN VKDLSKHSRQ NIQDSSLILA
PWDMFEEPYY WNQLRKLTCA ANVPNDPGRA FAEWLESSLN SLGDANQALL DNEAGFWKFW
KGLRAKQSGY DRFEGFMTRA SKKTEMAAQR KAEKEKAAAE AAAADKRKLD EVEQSDSDGD
HKPSQTPVSK ANEPAPADAG PTIAPDQTKA DTAPPQDDGW EKELDDFQNM ETIPALLHMF
SFRRIIVDEF TYIPGKTLLA LLKLQSDSRW LLSGTPPIHS YDSVNTMAKL LGTRISTYDE
GSGKFAFGKD GSKMTRDRSD AQEFQSYHTL RSSAYTNTVY RRTSLFSELF IRKNQAAVVL
KPRHEHFEYF DLSPSEMITY MEVDQLVEEQ DTVFNKKPPK PNAAAKGNGN QKPDDNNGGD
GEPADAAEDD DAGNDQMVTF VDRLKTAVEQ KPSPDYARMC AAPILAQSLE GIPENKIGSE
GQILQHLAES HKELLVARSE LLLQWFQEVW YIALGSPGQR AVCTPAFYDF MYDVKNGALP
DRDVLPIITQ LFWNAKQDPK KPARKLRPSR PPKPEPEPKK AKLQDKAAQA AQTKKDLENE
MNLRIDRVHV LIRDLARGFC RLRLLELVSA LVDKDGMLLP KCLGCGNATP DGQSIQISTS
CGHIVACEQC SEMGTYTETP CCVCFSPDQI KPASHFVAEV MEPKGKGKGK AKAVSVTSDD
VVRVGEGSRM MKAMAIIQGF KAKRELGLVF VQFPEVKDAL VRACQRAGLA SIDGFKYTQN
GVGKFQRAAE ALSRGQEPGA WLLILKTDSA DAAGWNLHMA NHVLFLSPLL VSSREERDAT
MEQAVGRSRR PRQQKEVHVY HLAARATMEE RMVASLRQV
//
