ID   H6C471_EXODN            Unreviewed;       305 AA.
AC   H6C471;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=NmrA-like domain-containing protein {ECO:0000259|Pfam:PF05368};
GN   ORFNames=HMPREF1120_05625 {ECO:0000313|EMBL:EHY57596.1};
OS   Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS   yeast) (Wangiella dermatitidis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY57596.1, ECO:0000313|Proteomes:UP000007304};
RN   [1] {ECO:0000313|EMBL:EHY57596.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY57596.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA   Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NmrA-type oxidoreductase family.
CC       {ECO:0000256|ARBA:ARBA00006328}.
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DR   EMBL; JH226134; EHY57596.1; -; Genomic_DNA.
DR   RefSeq; XP_009158057.1; XM_009159809.1.
DR   AlphaFoldDB; H6C471; -.
DR   STRING; 858893.H6C471; -.
DR   GeneID; 20310264; -.
DR   VEuPathDB; FungiDB:HMPREF1120_05625; -.
DR   eggNOG; ENOG502S0JD; Eukaryota.
DR   HOGENOM; CLU_007383_8_4_1; -.
DR   InParanoid; H6C471; -.
DR   OMA; MALAPCP; -.
DR   OrthoDB; 315135at2759; -.
DR   Proteomes; UP000007304; Unassembled WGS sequence.
DR   CDD; cd05251; NmrA_like_SDR_a; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR008030; NmrA-like.
DR   PANTHER; PTHR42748; NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER; 1.
DR   PANTHER; PTHR42748:SF35; NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11740); 1.
DR   Pfam; PF05368; NmrA; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007304}.
FT   DOMAIN          6..245
FT                   /note="NmrA-like"
FT                   /evidence="ECO:0000259|Pfam:PF05368"
SQ   SEQUENCE   305 AA;  33823 MW;  318354C3000AE9E7 CRC64;
     MTTRNILVTG ATGKQGGAVV RALLDHPPPF DYQILAVTRK STSASARSLA SNPKVTIIEG
     SLNDPESIFK KAGGIGAVWG VFCVTIPSFK KEVEDAEVTQ GNGLVDAAVA HDVKHFVYTS
     VDRGGPDQSD VYATDIPHFV SKYNVEKHLR EKARGTGMSY TMLRPVAFMD NLTPNLPGRI
     FATMWASLGD KPLQMVASKD IGIFAAQAFA ASEKEEYHNK AISIAGDELT QARANEIFWT
     VLGRPMPRSY NFMATLLKKM IPEMAKMFQW FADQGYGCDI FYCRQLNKDM LDFETWLREE
     SGFKR
//