ID H6C9H1_EXODN Unreviewed; 1048 AA.
AC H6C9H1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Ca2+-transporting ATPase {ECO:0000313|EMBL:EHY59880.1};
GN ORFNames=HMPREF1120_07859 {ECO:0000313|EMBL:EHY59880.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY59880.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY59880.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY59880.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH226136; EHY59880.1; -; Genomic_DNA.
DR RefSeq; XP_009160341.1; XM_009162093.1.
DR AlphaFoldDB; H6C9H1; -.
DR STRING; 858893.H6C9H1; -.
DR GeneID; 20312498; -.
DR VEuPathDB; FungiDB:HMPREF1120_07859; -.
DR eggNOG; KOG0202; Eukaryota.
DR HOGENOM; CLU_002360_3_3_1; -.
DR InParanoid; H6C9H1; -.
DR OMA; KMHACET; -.
DR OrthoDB; 203629at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0030001; P:metal ion transport; IEA:UniProt.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF29; SECRETORY PATHWAY CALCIUM ATPASE, ISOFORM G; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 332..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 888..908
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 938..954
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 975..993
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1005..1023
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..111
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1048 AA; 113534 MW; 87ECF6DF5076733D CRC64;
MSTLSVPALP FVKPDSSPKR ARSPAPYADT FTSITSSYAL LSPQQTADRL QTSLTHGLSQ
SEAQARLARD GPNELPHEEE EPLWLRFLKQ FKETLILLLL ASAAISLFIG NKDDAVSIAL
AVTIVVTVGF VQEYRSEKSL EALNRLVPYH AHVRRTGLRP WMQASRLPIP EDEIELEPLS
NGLTSEDKTS ATIPASQLVV GDLVIFSTGD RIPADIRITR SSELTIDESN LTGENEPVEK
HAAALDRAAP SFAHHGTPEP LNAAGTVGAD VRLNDQHNIA FMGTLVRSGH GEGVVIATGG
NTEFGTISLS LQEIEAPRTP LQQSMDLLGK QLSYMSFVVI GIIMIIGLLQ GKKPLDLFTI
GVSLAVAAIP EGLPIIVTVT LALGVLRMAK RGAIVRKLPS VETLGSVNVV CSDKTGTLTM
NHMTVTEMWH FDMPKPFGVD TSAEPSAATR AILRIGNISN NGRLSHTTSG TPATAASAAV
LSSTRDRSST NTRSRWLGQP TDIAMLDLLD AFGEDDIREQ IGHRTAETPF SSERKWMGVV
IGNALGELAN DHGTSTETAY IKGSIEQVLS RSDTYLTRDG QEVILDETRR QQALAAAQTM
AEEGLRVIAF ASGVVRNKQR QPSRSPTPSR ADKKPEETDI FQGLCFAGLV GMNDPPRKDV
HRSIRRLMSG GVKVIMITGD AETTAVAIAK NLGMPINQGS SASRSVLRGD ELDRMSEQEL
AEAIGKTTVF ARTSPDHKMK IIRALQARGD VVAMTGDGVN DAPALKKADI GIAMGMLGTD
VAKEAADMIL TDDDFSTILR AIEQGKGIFY NIQNFITFQL STSVAALTLV LLSTMFGFKN
PLNAMQILWI NILMDGPPAQ SLGVEPVDPR VMTQPPRPRN ANVLTKRLIR RVLTSAFIIM
IGTLTVYIHE MAVVDDPSAG VTDDGAPLRT RMVTKRDTTM TFTTFVLFDM FNALTCRSEA
KSVLFGEIKL FGNKMFNYAV AGSLAGQLCV IYLPFLQRVF QTEALGLGDL LALVCIASTV
FWADEFRKWI ERRRAAGYLP SVGYSASV
//
