ID H6CB76_EXODN Unreviewed; 549 AA.
AC H6CB76;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=HMPREF1120_08963 {ECO:0000313|EMBL:EHY61023.1};
OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS yeast) (Wangiella dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY61023.1, ECO:0000313|Proteomes:UP000007304};
RN [1] {ECO:0000313|EMBL:EHY61023.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY61023.1};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR EMBL; JH226137; EHY61023.1; -; Genomic_DNA.
DR RefSeq; XP_009161484.1; XM_009163236.1.
DR AlphaFoldDB; H6CB76; -.
DR STRING; 858893.H6CB76; -.
DR ESTHER; exodn-h6cb76; Fungal_carboxylesterase_lipase.
DR GeneID; 20313602; -.
DR VEuPathDB; FungiDB:HMPREF1120_08963; -.
DR eggNOG; KOG1516; Eukaryota.
DR HOGENOM; CLU_006586_14_4_1; -.
DR InParanoid; H6CB76; -.
DR OMA; SWPQFDY; -.
DR OrthoDB; 1387367at2759; -.
DR Proteomes; UP000007304; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR43142; CARBOXYLIC ESTER HYDROLASE; 1.
DR PANTHER; PTHR43142:SF11; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000007304}.
FT DOMAIN 14..457
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 549 AA; 59638 MW; E9EEF711F4A42B0A CRC64;
MSSQSVVLRH PSIGPIHGLD RGNGVHQFLG IQYATLQDRL AEAQLKTTYQ TPVDAANYGP
SSFSPPNGFD NETRLFIQQP LPQPPTVPSD LNCLNLNITV PASSDSTKRL PVFIWTHGGG
FVVGANSWPH YDHARVVRLA AEHGIPVIGV GINFRLGLPG LLTSEELRRK GYKPNNLLHD
QRTAFQWVKQ HIAGFGGDPD IITVIGESTG AVATTLHLYS QQKLFNRAIA TGGSCLLIPL
FSPEDHERTY QQVLSILGLA ELGPGERIQR LLSMPMDEII ARLPPSVALL PMIDGDIIPQ
RPTYVTIADQ EDRSMPGKQW AEGLIIGDSQ FDSSTLATMM AHLKPNIRKR FSASIRNSLS
TTTPDVAEAL LEAYGFNSPA LADPAADDEA AFLRFLHFAN DIGYYAATIS FARGWSSSSS
PSSSKALVFF FNEPNPWPGP FQGQATHVLD VVFLFQNFND KLPPAQRAAA EGFALDLMAF
VSGKTPWNPY TPGARTAKVF GPSLTDAVTK VVADAESVET GRRAAILELG KQVGLDKLAE
AFGRFNMGL
//
