ID   H6CBI5_EXODN            Unreviewed;      1099 AA.
AC   H6CBI5;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN   ORFNames=HMPREF1120_09068 {ECO:0000313|EMBL:EHY61132.1};
OS   Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black
OS   yeast) (Wangiella dermatitidis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=858893 {ECO:0000313|EMBL:EHY61132.1, ECO:0000313|Proteomes:UP000007304};
RN   [1] {ECO:0000313|EMBL:EHY61132.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NIH/UT8656 {ECO:0000313|EMBL:EHY61132.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Wang Z., Hunicke-Smith S., Szanislo P.J., Earl A., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA   Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA   Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Exophiala (Wangiella) dermatitidis NIH/UT8656.";
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; JH226137; EHY61132.1; -; Genomic_DNA.
DR   RefSeq; XP_009161593.1; XM_009163345.1.
DR   AlphaFoldDB; H6CBI5; -.
DR   STRING; 858893.H6CBI5; -.
DR   GeneID; 20313707; -.
DR   VEuPathDB; FungiDB:HMPREF1120_09068; -.
DR   eggNOG; ENOG502QRAT; Eukaryota.
DR   HOGENOM; CLU_003938_0_0_1; -.
DR   InParanoid; H6CBI5; -.
DR   OMA; DRWVMSI; -.
DR   OrthoDB; 1360556at2759; -.
DR   Proteomes; UP000007304; Unassembled WGS sequence.
DR   GO; GO:1902657; P:protein localization to prospore membrane; IEA:InterPro.
DR   InterPro; IPR040345; Mug56/Spo71.
DR   InterPro; IPR039486; Mug56/Spo71_PH.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR029217; Spo7_2_N.
DR   PANTHER; PTHR28076:SF1; PROSPORE MEMBRANE ADAPTER PROTEIN SPO71; 1.
DR   PANTHER; PTHR28076; SPORULATION-SPECIFIC PROTEIN 71; 1.
DR   Pfam; PF15404; PH_4; 1.
DR   Pfam; PF15407; Spo7_2_N; 1.
DR   SMART; SM00233; PH; 2.
DR   SMART; SM01316; Spo7_2_N; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007304}.
FT   DOMAIN          605..815
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          78..140
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          154..253
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          750..773
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1006..1042
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..233
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        238..253
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1006..1038
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1099 AA;  124693 MW;  EDA0046B9F11C9E8 CRC64;
     MPVGSSTTRG HDANALDPDS YTAHRLKHAF PEHLHLTSRR FFIGPIPEGW LNSNRKSWYK
     RRLELSSYSS RQQSFRAAAD GGAHHRTLTG LDGPSTAARM SFSFPQPEDV YDAASSAEDS
     SAAEEVDDEP QVNEARNVEP ISTNEIPLIV GIEDQDEEGN RVPKALPIPA DTGLDGTSEH
     RGGVRFARSP KPDSFKTAQE HLGGSSSKSV TPLHRYEHPD QPTDPDSDPE EPPSNRGSFD
     PSGATQEDIE TSSRTALLAP EGEGLHDRSL QQHDPAPLQD ESTYQLVRSN TGVRFKISEE
     VHQRRHRIET KASRAKHRVK RLRRDMLREG TIVKMERMLV RCEITKNQVP DEFDENESLK
     IESRVVEKWR EFVVVARKSK KQDDVDFRLQ IYKTRVIPEI EDEKTKKKPL HEVKLDPKTT
     RVNLYSSLDK TVVIWHPYKA GTRIFVMRPI STAHSVEWYT FLRDALGWQR PDTLHVNVPD
     LDVVLKLEKP FEGLEAAGLN ATDEETAIAR TVAAERAVAG EIISQCMNML RRDREWSSVI
     KLWQETAKMG LAWKRYDRLE WVYGVHEQKM YGSMAMEHSH DLELRPKKHY PTSARGRKGK
     LHEEPPPIEG FLIRLTSQKG AHQRLGKAFF KRLYFSTHSQ YLMFNRPAKA TPPHPPRLAT
     IGGNTVPSAR EIVEKTPLMY DIEPYKLHND GISWLSSGNP ATVRSHDREA VEEARRNVAN
     VLESDGLINM CYIRQVRVIK WGASPADDNL EEGSSSDVDF HQNVPDTRGE DGATKQIDDD
     RVFEILLDNG LVIRLQAYSK KTRDEWISRL KKLVKYWKLR MAAEMDTYKA VRKANLAELN
     IDEELEAIIG QYAKKWEVSR SEASPELYNL CGISSCRSIT MSGSLYLKPH RRAAFHRSQV
     ILCGGKLLIY QATVRKSTGA QVRHIHQEKQ QVVDLKDCYV YSGLIVEDDL LYQNTTFDAN
     HPGMASLPRV YLDDGWTSAD VDVMTCFVVW MNRKKGWFRT AAAVAEEQTQ PQSQPQSDGP
     VDVTTESNTK NSAGGSRGNT RAKLRRVGQL GVPGRGMVFK CRSRAERDHW VLSVASEIER
     VMEQEAQNMG DQGEFRFDK
//