ID H6LDS6_ACEWD Unreviewed; 391 AA.
AC H6LDS6;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=N-acetylglucosamine-6-phosphate 2-epimerase/N-acetylglucosamine-6-phosphatase NeuC {ECO:0000313|EMBL:AFA49240.1};
DE EC=5.1.3.14 {ECO:0000313|EMBL:AFA49240.1};
GN Name=neuC {ECO:0000313|EMBL:AFA49240.1};
GN OrderedLocusNames=Awo_c24830 {ECO:0000313|EMBL:AFA49240.1};
OS Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655
OS / WB1).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Acetobacterium.
OX NCBI_TaxID=931626 {ECO:0000313|EMBL:AFA49240.1, ECO:0000313|Proteomes:UP000007177};
RN [1] {ECO:0000313|Proteomes:UP000007177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1
RC {ECO:0000313|Proteomes:UP000007177};
RA Poehlein A., Schmidt S., Kaster A.-K., Goenrich M., Vollmers J.,
RA Thuermer A., Gottschalk G., Thauer R.K., Daniel R., Mueller V.;
RT "Complete genome sequence of Acetobacterium woodii.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFA49240.1, ECO:0000313|Proteomes:UP000007177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1
RC {ECO:0000313|Proteomes:UP000007177};
RX PubMed=22479398; DOI=10.1371/journal.pone.0033439;
RA Poehlein A., Schmidt S., Kaster A.K., Goenrich M., Vollmers J., Thurmer A.,
RA Bertsch J., Schuchmann K., Voigt B., Hecker M., Daniel R., Thauer R.K.,
RA Gottschalk G., Muller V.;
RT "An ancient pathway combining carbon dioxide fixation with the generation
RT and utilization of a sodium ion gradient for ATP synthesis.";
RL PLoS ONE 7:E33439-E33439(2012).
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DR EMBL; CP002987; AFA49240.1; -; Genomic_DNA.
DR RefSeq; WP_014356840.1; NC_016894.1.
DR AlphaFoldDB; H6LDS6; -.
DR STRING; 931626.Awo_c24830; -.
DR KEGG; awo:Awo_c24830; -.
DR eggNOG; COG0381; Bacteria.
DR HOGENOM; CLU_061127_0_0_9; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000007177; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006047; P:UDP-N-acetylglucosamine metabolic process; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR020004; UDP-GlcNAc_Epase.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR03568; NeuC_NnaA; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF3; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:AFA49240.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007177}.
FT DOMAIN 23..368
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 391 AA; 44152 MW; 6FD9AE829AE7018B CRC64;
MKKICVITST RAEYGLLKNL IRKIDDDAEL DLCLVVTGTH LSSEFGMTIH EIEEDGFPIA
ERIDILLSSD TMAAISKTMG LALILFSDVF QRQNPDMLIV LGDRYELIPI CSCAMNAQVP
ISHISGGETT EGVIDECVRH CITKMSYLHF PACELYRKRI IQLGETPNRV FNFGDIGVEV
IRTIDLYEKK EMEEIVGFSL ERRYGCITFH PITLESELLE KQINELLIAI TEFPKMHFIF
TKSNSDANSR MINKKIDEYV AKHKNCVAFK SLGIRRYLSC VKYADVIIGN SSSGIVEAPS
FGIPSVNIGD RQKGRLQASS VINCRPEAND IINAIDLSQT ESFRIRAKNT INPYASGNTV
ECIINVIKDH LFEDKIDLKK KFYDVNFEVK E
//
