ID H6LHC8_ACEWD Unreviewed; 957 AA.
AC H6LHC8;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:AFA49638.1};
GN OrderedLocusNames=Awo_c29040 {ECO:0000313|EMBL:AFA49638.1};
OS Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655
OS / WB1).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Acetobacterium.
OX NCBI_TaxID=931626 {ECO:0000313|EMBL:AFA49638.1, ECO:0000313|Proteomes:UP000007177};
RN [1] {ECO:0000313|Proteomes:UP000007177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1
RC {ECO:0000313|Proteomes:UP000007177};
RA Poehlein A., Schmidt S., Kaster A.-K., Goenrich M., Vollmers J.,
RA Thuermer A., Gottschalk G., Thauer R.K., Daniel R., Mueller V.;
RT "Complete genome sequence of Acetobacterium woodii.";
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFA49638.1, ECO:0000313|Proteomes:UP000007177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1
RC {ECO:0000313|Proteomes:UP000007177};
RX PubMed=22479398; DOI=10.1371/journal.pone.0033439;
RA Poehlein A., Schmidt S., Kaster A.K., Goenrich M., Vollmers J., Thurmer A.,
RA Bertsch J., Schuchmann K., Voigt B., Hecker M., Daniel R., Thauer R.K.,
RA Gottschalk G., Muller V.;
RT "An ancient pathway combining carbon dioxide fixation with the generation
RT and utilization of a sodium ion gradient for ATP synthesis.";
RL PLoS ONE 7:E33439-E33439(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; CP002987; AFA49638.1; -; Genomic_DNA.
DR AlphaFoldDB; H6LHC8; -.
DR STRING; 931626.Awo_c29040; -.
DR KEGG; awo:Awo_c29040; -.
DR eggNOG; COG0840; Bacteria.
DR eggNOG; COG5000; Bacteria.
DR HOGENOM; CLU_000445_107_12_9; -.
DR Proteomes; UP000007177; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 1.20.120.1530; -; 2.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF18947; HAMP_2; 3.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 3.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 2.
DR PROSITE; PS50192; T_SNARE; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007177};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 238..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 259..312
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 614..666
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 671..900
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT DOMAIN 830..892
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT REGION 933..957
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 957 AA; 102967 MW; 7A23A0F628C8B26D CRC64;
MEDYAISSSK QVGAVISGNL STLNEVAMGS SVASMNWPAQ VATLTDDVNR LGYEDMAIVD
MNGHGKYVIN GGEFDTGSEP WFKGAYAGKN TISDVTISKV TNKPSVFETV PIKNNSSQVV
GLLIGRRDPN FLQDVVSNMG AEGDREYGFI IANDGMMMAH PNGELIQSET NIFKEDSFVS
FVASYNELGT NKTGVIDYDY LGNAKIATAA PITGTDWILF YTIYESDLMA PITDLRNITF
IISLIVLVLG GFIGFAMSNR ISKPIVKIKN ALDQLALGDV EISVPDINTK DEVADLVTSF
RTMITNRKDQ AEVAQRLAEG DFSVEIIPQS DKDVLSYSMI AVIKQMNKLY DGIVEIAGEA
RDGHLDFRGN PDLYPGSYKD FITGLNSVID TFISPIKVSN AYMKQIGQGE IPSKITDPYK
GDFNILKNNI NACIDGLDAL VEGNRILGKM RLNDFSEKIE AEYLGIYGEI ANSINEVHFR
FDHIVSIAHN IANGDLCDLQ DLNTIGKRSD LDTLNPSLIK MIENISMLVA ETESMAQKAV
EGDLSNRGDA DKFKGEFANV VSGINQTLDA ILAPLVEASA VLGELSGGNL ATSMQGNYQG
DNAKIKNDLN QTIAFLKRYV DEITVTLEAL GQGNLNQNIT SDYQGDFLAI KIALNNITNN
LSSTMSDIDI AAGQVEVGAH QISDGGQALS QGTTEQASAI QELTASIEEV ASETKKNAVS
ANEAKDVAIK VRNSAQNSNN EMGKMVHAMV DINDSSNNIS KIIKVIDDIA FQTNILALNA
AVEAARAGQQ GKGFAVVAEE VRSLAARSAE AAKETTALIE GSIEKVSVGS KIADETAESL
NEILTQIEKV TNLVGNIAQA SNDQATEIAQ ISQGIEQVSE VVQTNSATAE ESAAASEELS
GQAELLKQMV GTFTLKNLDG PKLSGSPQIA LNVQKNHPEN PISVPQIRLD DSKTDKY
//
