ID H6MU62_GORPV Unreviewed; 407 AA.
AC H6MU62;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=citrate synthase (unknown stereospecificity) {ECO:0000256|ARBA:ARBA00012972};
DE EC=2.3.3.16 {ECO:0000256|ARBA:ARBA00012972};
GN OrderedLocusNames=GPOL_c04690 {ECO:0000313|EMBL:AFA71539.1};
OS Gordonia polyisoprenivorans (strain DSM 44266 / VH2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1112204 {ECO:0000313|EMBL:AFA71539.1, ECO:0000313|Proteomes:UP000009154};
RN [1] {ECO:0000313|EMBL:AFA71539.1, ECO:0000313|Proteomes:UP000009154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44266 / VH2 {ECO:0000313|Proteomes:UP000009154};
RX PubMed=22327575; DOI=10.1128/AEM.07969-11;
RA Hiessl S., Schuldes J., Thurmer A., Halbsguth T., Broker D., Angelov A.,
RA Liebl W., Daniel R., Steinbuchel A.;
RT "Involvement of two latex-clearing proteins during rubber degradation and
RT insights into the subsequent degradation pathway revealed by the genome
RT sequence of Gordonia polyisoprenivorans strain VH2.";
RL Appl. Environ. Microbiol. 78:2874-2887(2012).
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC {ECO:0000256|ARBA:ARBA00005163}.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566}.
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DR EMBL; CP003119; AFA71539.1; -; Genomic_DNA.
DR RefSeq; WP_014358541.1; NC_016906.1.
DR AlphaFoldDB; H6MU62; -.
DR STRING; 1112204.GPOL_c04690; -.
DR KEGG; gpo:GPOL_c04690; -.
DR eggNOG; COG0372; Bacteria.
DR HOGENOM; CLU_025068_1_0_11; -.
DR UniPathway; UPA00223; -.
DR Proteomes; UP000009154; Chromosome.
DR GO; GO:0036440; F:citrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR041657; HTH_17.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF4; CITRATE SYNTHASE, PEROXISOMAL; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR Pfam; PF12728; HTH_17; 1.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009154}.
FT DOMAIN 20..51
FT /note="Helix-turn-helix"
FT /evidence="ECO:0000259|Pfam:PF12728"
SQ SEQUENCE 407 AA; 43636 MW; D0B65A138F688123 CRC64;
MTRAHTRRFP TPIRHDGRDY LTTEQVAKVL GVKLSTVYAY VSRGRLHSSR IAGYDGSMFA
VDEVDGLLQG SRHRPPAGVA ERIRTQLTYL HDDRLHYRGH DVADLARTTG YEDVAQLLWG
EPWTAAPPAQ GIGAAVRRVA GTNSRGLDRI RLTVDLLGAR DPLRHHIEPA AVTEKATRVL
VTAVDALAPG ESEGSLAQRL WPRLTDEPAT PRAVKVLNAA LVALADHDLA AGTVAARVAA
SARGSVYAVI GAGLGAFDGP MHGGATTLAY RFLADALDDP TAAIADALYA DSRIPGTGHV
IYRARDPRAT VLLEMLARSG GGDRRVQPAV TTIVEALGPS TFVNSDLALA ALALRYRMRP
DAAETIFALA RIAGWIAHAL EEYQAPRLRF RPEGVYTGVR PSGAHAT
//
