ID H6MZ14_GORPV Unreviewed; 321 AA.
AC H6MZ14;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Hexose kinase, 1-phosphofructokinase family {ECO:0000313|EMBL:AFA73155.1};
DE EC=2.7.1.- {ECO:0000313|EMBL:AFA73155.1};
GN OrderedLocusNames=GPOL_c21160 {ECO:0000313|EMBL:AFA73155.1};
OS Gordonia polyisoprenivorans (strain DSM 44266 / VH2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1112204 {ECO:0000313|EMBL:AFA73155.1, ECO:0000313|Proteomes:UP000009154};
RN [1] {ECO:0000313|EMBL:AFA73155.1, ECO:0000313|Proteomes:UP000009154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44266 / VH2 {ECO:0000313|Proteomes:UP000009154};
RX PubMed=22327575; DOI=10.1128/AEM.07969-11;
RA Hiessl S., Schuldes J., Thurmer A., Halbsguth T., Broker D., Angelov A.,
RA Liebl W., Daniel R., Steinbuchel A.;
RT "Involvement of two latex-clearing proteins during rubber degradation and
RT insights into the subsequent degradation pathway revealed by the genome
RT sequence of Gordonia polyisoprenivorans strain VH2.";
RL Appl. Environ. Microbiol. 78:2874-2887(2012).
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000256|RuleBase:RU003704}.
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DR EMBL; CP003119; AFA73155.1; -; Genomic_DNA.
DR RefSeq; WP_014359828.1; NC_016906.1.
DR AlphaFoldDB; H6MZ14; -.
DR STRING; 1112204.GPOL_c21160; -.
DR KEGG; gpo:GPOL_c21160; -.
DR eggNOG; COG1105; Bacteria.
DR HOGENOM; CLU_050013_0_0_11; -.
DR Proteomes; UP000009154; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01164; FruK_PfkB_like; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR002139; Ribo/fructo_kinase.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR017583; Tagatose/fructose_Pkinase.
DR NCBIfam; TIGR03168; 1-PFK; 1.
DR PANTHER; PTHR46566:SF5; 1-PHOSPHOFRUCTOKINASE; 1.
DR PANTHER; PTHR46566; 1-PHOSPHOFRUCTOKINASE-RELATED; 1.
DR Pfam; PF00294; PfkB; 1.
DR PIRSF; PIRSF000535; 1PFK/6PFK/LacC; 1.
DR PRINTS; PR00990; RIBOKINASE.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU003704};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000009154};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR000535}.
FT DOMAIN 23..301
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 321 AA; 32822 MW; 899EDE786BEDB831 CRC64;
MILTVTANPS LDRTLEIAGP LQRGEVQRTV GVRAEPGGKG VNVSRVIAEA GLTTLAILPA
RNGDPLLTAL DQVGLRHEAL AVPGEVRSNI TIAEPDGTTT KINASGQFLD DRQVRALTDL
VLARAAGADW VALCGSLPPG VADDWYRVLA DQLIARGHRV AIDTSGAPLT AAVTGRVDLI
KPNEYELAEV SGADPEILRH AAAEGDLSPI VSASADMAHR IGGAVLATLG AAGALLTTES
GSWFATPPPI VPRSTVGAGD SSLAGYLIAE TRGADEPGRL RSAVAYGAAA AALAGTQPPR
PDHLDPDRVV ITDLAGAAPT P
//
