ID H6N4P1_GORPV Unreviewed; 673 AA.
AC H6N4P1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=HAD-superfamily hydrolase, subfamily IIA {ECO:0000313|EMBL:AFA73623.1};
GN OrderedLocusNames=GPOL_c25970 {ECO:0000313|EMBL:AFA73623.1};
OS Gordonia polyisoprenivorans (strain DSM 44266 / VH2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1112204 {ECO:0000313|EMBL:AFA73623.1, ECO:0000313|Proteomes:UP000009154};
RN [1] {ECO:0000313|EMBL:AFA73623.1, ECO:0000313|Proteomes:UP000009154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44266 / VH2 {ECO:0000313|Proteomes:UP000009154};
RX PubMed=22327575; DOI=10.1128/AEM.07969-11;
RA Hiessl S., Schuldes J., Thurmer A., Halbsguth T., Broker D., Angelov A.,
RA Liebl W., Daniel R., Steinbuchel A.;
RT "Involvement of two latex-clearing proteins during rubber degradation and
RT insights into the subsequent degradation pathway revealed by the genome
RT sequence of Gordonia polyisoprenivorans strain VH2.";
RL Appl. Environ. Microbiol. 78:2874-2887(2012).
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DR EMBL; CP003119; AFA73623.1; -; Genomic_DNA.
DR RefSeq; WP_014360205.1; NC_016906.1.
DR AlphaFoldDB; H6N4P1; -.
DR STRING; 1112204.GPOL_c25970; -.
DR KEGG; gpo:GPOL_c25970; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG0647; Bacteria.
DR HOGENOM; CLU_024300_0_0_11; -.
DR Proteomes; UP000009154; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.290; -; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR041065; GNAT-like.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR006357; HAD-SF_hydro_IIA.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR NCBIfam; TIGR01460; HAD-SF-IIA; 1.
DR PANTHER; PTHR19288; 4-NITROPHENYLPHOSPHATASE-RELATED; 1.
DR PANTHER; PTHR19288:SF96; D-GLYCEROL 3-PHOSPHATE PHOSPHATASE; 1.
DR Pfam; PF18407; GNAT_like; 1.
DR Pfam; PF13344; Hydrolase_6; 1.
DR Pfam; PF13242; Hydrolase_like; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AFA73623.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009154}.
FT DOMAIN 605..670
FT /note="GCN5-related N-acetyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF18407"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 673 AA; 71185 MW; 4F55C6A1C9788CE1 CRC64;
MNDRDRTRGR RQRPDRADQS GRPHREGRQR TDGPTDPALP EDVVASDLDP DTRRDLLSLE
KGTAERVARH LVMVAELLYE DADLALEHAR AARRRAARVG VVRETAGVAA YNAGQWQEAI
SELRAARRIT GSSALLPLIA DAERGLGRPE RAIEIARSEE GRALRDDEAT EMRIVEAGAR
LDIGEPEKAL VTLQLEDLSP SRTGTAAARL FYAYASALEA AGRLDEATTW FMNASAADTE
DATDAEFRLM EISVGSAEPD VDPAHEDQQD SGAAIAETEP ASEPEPAPRS ESLGSTESQP
GSVRQASVAE PESEQGSEIA VAPARETEPV PPPPAPARVV DAYDALLLDL DGTVFAGKSP
IPGVPETLER IDVTTIFVTN NASRRPDAVA EHLRSMGFTA TPEQVVTSAQ SAARLLSEHL
EPGSRALVLG TDGLAQEVRE VGIAVTRSAD DRPLAVIQGF SPETSWESLS EAALAIRAGA
LWVATNVDAT LPSERGLLVG NGSLVAAVAN ATGQEPLVAG KPAAPLMADA INRSGADTPL
VVGDRLDTDI QGAHSVGLDS LLVLSGVSTA TDLLAAPPQQ RPTFVCADLS GVLDPADSLR
IADNDDWRIE QTGDTLTVSP VTEPPATLRL LPSLAARVWA LADADEIDLT EITITADDPT
TRSALEDLGL GAE
//
