ID   H6NK56_9BACL            Unreviewed;       382 AA.
AC   H6NK56;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=AdhB2 {ECO:0000313|EMBL:AFC31540.1};
GN   ORFNames=PM3016_4802 {ECO:0000313|EMBL:AFC31540.1};
OS   Paenibacillus mucilaginosus 3016.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1116391 {ECO:0000313|EMBL:AFC31540.1, ECO:0000313|Proteomes:UP000007523};
RN   [1] {ECO:0000313|EMBL:AFC31540.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3016 {ECO:0000313|EMBL:AFC31540.1};
RX   PubMed=22535950; DOI=10.1128/JB.00323-12;
RA   Ma M., Wang Z., Li L., Jiang X., Guan D., Cao F., Chen H., Wang X.,
RA   Shen D., Du B., Li J.;
RT   "Complete Genome Sequence of Paenibacillus mucilaginosus 3016, a Bacterium
RT   Functional as Microbial Fertilizer.";
RL   J. Bacteriol. 194:2777-2778(2012).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; CP003235; AFC31540.1; -; Genomic_DNA.
DR   RefSeq; WP_014371224.1; NC_016935.1.
DR   AlphaFoldDB; H6NK56; -.
DR   STRING; 1116391.PM3016_4802; -.
DR   KEGG; pmq:PM3016_4802; -.
DR   HOGENOM; CLU_026673_11_3_9; -.
DR   Proteomes; UP000007523; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08283; FDH_like_1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007523};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          8..380
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   382 AA;  41194 MW;  DD21B1E1A3148A63 CRC64;
     MKAVTYQGAK SVKVSEVPDA KLEQADDVLV RITTTAICGT DLHLYNGHLP GTPHGYVIGH
     EPVGIVEETG PEVTRVKKGD RVIIPATVAC GGCRYCRSDL ESLCDNGNPN ANAFGEPGGV
     LGYSEKYGGF AGAQAELLRV PYGNFMPFPV PPESELSDES LLFLSDILPT AYWSVENAGV
     MPGDTVVVLG CGPVGLLTQK CAKLKGAARI IAVDHVPYRL EHARATNGVE TFNFDETDNL
     EEHIKEITRG GADVVIDCVG MDGQKSVLEK VGTALKLQGG TLGPLRMAIH MVRKGGTVQL
     TGFYGMLYHA FPLGYMFERN ITLRMGSVPL VHYMPELYHL MRTGALDPAD VITHRLPLDE
     GERAYDLFAG KKDGAIKVLL KP
//