ID H6QZD1_NOCCG Unreviewed; 375 AA.
AC H6QZD1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Putative peptidase {ECO:0000313|EMBL:CCF64090.1};
GN OrderedLocusNames=NOCYR_3325 {ECO:0000313|EMBL:CCF64090.1};
OS Nocardia cyriacigeorgica (strain GUH-2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1127134 {ECO:0000313|EMBL:CCF64090.1, ECO:0000313|Proteomes:UP000008190};
RN [1] {ECO:0000313|EMBL:CCF64090.1, ECO:0000313|Proteomes:UP000008190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GUH-2 {ECO:0000313|EMBL:CCF64090.1,
RC ECO:0000313|Proteomes:UP000008190};
RX PubMed=22461543; DOI=10.1128/JB.00161-12;
RA Zoropogui A., Pujic P., Normand P., Barbe V., Beaman B., Beaman L.,
RA Boiron P., Colinon C., Deredjian A., Graindorge A., Mangenot S.,
RA Nazaret S., Neto M., Petit S., Roche D., Vallenet D., Rodriguez-Nava V.,
RA Richard Y., Cournoyer B., Blaha D.;
RT "Genome sequence of the human- and animal-pathogenic strain Nocardia
RT cyriacigeorgica GUH-2.";
RL J. Bacteriol. 194:2098-2099(2012).
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|RuleBase:RU000590}.
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DR EMBL; FO082843; CCF64090.1; -; Genomic_DNA.
DR RefSeq; WP_014351546.1; NC_016887.1.
DR AlphaFoldDB; H6QZD1; -.
DR STRING; 1127134.NOCYR_3325; -.
DR KEGG; ncy:NOCYR_3325; -.
DR eggNOG; COG0006; Bacteria.
DR HOGENOM; CLU_017266_4_1_11; -.
DR OrthoDB; 9806388at2; -.
DR Proteomes; UP000008190; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR46112:SF3; AMINOPEPTIDASE YPDF; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000590};
KW Reference proteome {ECO:0000313|Proteomes:UP000008190}.
FT DOMAIN 17..149
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 156..359
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 375 AA; 39970 MW; EF8717EA49262C24 CRC64;
MSSHTDSRFA ADVYADRLER AVQLMREAHL DALLITPGPD LRYLIGSAAD SFERLTCLVI
PADKGTPSVV VPKLELASLE GSAASDLGLQ VHDWVDGVDP YQIVKSALHV GSRVAVTDSM
PALHLIPLAE SFSGLPASAT PVLRELRMIK DAAEIEALRE AGAAIDRVHA RMGEWLLPGR
TEAEVAADIE QAIIAEGHTE AEFIIVGSGP NGAIPHHEKS ERRLQQGDVV VIDIGGPVAS
GYNSDCTRTY VLGEPRADVA TRYAELEEAQ AAAVAAVRPG VTAESVDAAA REPLRAAGLG
EAFLHRTGHG IGLSVHEEPY IVAGNELELR PGMAFSVEPG IYFRGEWGAR IEDIVVVTED
GAESMNQRPH GLTVL
//
