ID H6R3L5_NOCCG Unreviewed; 123 AA.
AC H6R3L5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=ATP-dependent Clp protease adapter protein ClpS {ECO:0000256|HAMAP-Rule:MF_00302};
GN Name=clpS {ECO:0000256|HAMAP-Rule:MF_00302,
GN ECO:0000313|EMBL:CCF61972.1};
GN OrderedLocusNames=NOCYR_1170 {ECO:0000313|EMBL:CCF61972.1};
OS Nocardia cyriacigeorgica (strain GUH-2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1127134 {ECO:0000313|EMBL:CCF61972.1, ECO:0000313|Proteomes:UP000008190};
RN [1] {ECO:0000313|EMBL:CCF61972.1, ECO:0000313|Proteomes:UP000008190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GUH-2 {ECO:0000313|EMBL:CCF61972.1,
RC ECO:0000313|Proteomes:UP000008190};
RX PubMed=22461543; DOI=10.1128/JB.00161-12;
RA Zoropogui A., Pujic P., Normand P., Barbe V., Beaman B., Beaman L.,
RA Boiron P., Colinon C., Deredjian A., Graindorge A., Mangenot S.,
RA Nazaret S., Neto M., Petit S., Roche D., Vallenet D., Rodriguez-Nava V.,
RA Richard Y., Cournoyer B., Blaha D.;
RT "Genome sequence of the human- and animal-pathogenic strain Nocardia
RT cyriacigeorgica GUH-2.";
RL J. Bacteriol. 194:2098-2099(2012).
CC -!- FUNCTION: Involved in the modulation of the specificity of the ClpAP-
CC mediated ATP-dependent protein degradation. {ECO:0000256|HAMAP-
CC Rule:MF_00302}.
CC -!- SUBUNIT: Binds to the N-terminal domain of the chaperone ClpA.
CC {ECO:0000256|HAMAP-Rule:MF_00302}.
CC -!- SIMILARITY: Belongs to the ClpS family. {ECO:0000256|HAMAP-
CC Rule:MF_00302}.
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DR EMBL; FO082843; CCF61972.1; -; Genomic_DNA.
DR RefSeq; WP_014349439.1; NC_016887.1.
DR AlphaFoldDB; H6R3L5; -.
DR STRING; 1127134.NOCYR_1170; -.
DR KEGG; ncy:NOCYR_1170; -.
DR eggNOG; COG2127; Bacteria.
DR HOGENOM; CLU_153743_0_0_11; -.
DR OrthoDB; 162238at2; -.
DR Proteomes; UP000008190; Chromosome.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1390.10; -; 1.
DR HAMAP; MF_00302; ClpS; 1.
DR InterPro; IPR022935; ClpS.
DR InterPro; IPR003769; ClpS_core.
DR InterPro; IPR014719; Ribosomal_bL12_C/ClpS-like.
DR Pfam; PF02617; ClpS; 1.
DR SUPFAM; SSF54736; ClpS-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:CCF61972.1};
KW Protease {ECO:0000313|EMBL:CCF61972.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008190}.
FT DOMAIN 46..118
FT /note="Adaptor protein ClpS core"
FT /evidence="ECO:0000259|Pfam:PF02617"
SQ SEQUENCE 123 AA; 13614 MW; 2D481562C1206186 CRC64;
MALCNTAPRY RTDAAPAGAV AVAANATLSA QATPEAVEYT EILEAEDRPW VTVVWDDPVN
LMHYVTYIFQ KLFGYSKAKA TELMLKVHNE GKAVVSSGSR DKMEQDVRRL HAAGLWATMQ
RDD
//
