ID H6R4U1_NOCCG Unreviewed; 498 AA.
AC H6R4U1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Putative cobyrinic acid a,c-diamide synthase {ECO:0000313|EMBL:CCF64566.1};
GN OrderedLocusNames=NOCYR_3803 {ECO:0000313|EMBL:CCF64566.1};
OS Nocardia cyriacigeorgica (strain GUH-2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1127134 {ECO:0000313|EMBL:CCF64566.1, ECO:0000313|Proteomes:UP000008190};
RN [1] {ECO:0000313|EMBL:CCF64566.1, ECO:0000313|Proteomes:UP000008190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GUH-2 {ECO:0000313|EMBL:CCF64566.1,
RC ECO:0000313|Proteomes:UP000008190};
RX PubMed=22461543; DOI=10.1128/JB.00161-12;
RA Zoropogui A., Pujic P., Normand P., Barbe V., Beaman B., Beaman L.,
RA Boiron P., Colinon C., Deredjian A., Graindorge A., Mangenot S.,
RA Nazaret S., Neto M., Petit S., Roche D., Vallenet D., Rodriguez-Nava V.,
RA Richard Y., Cournoyer B., Blaha D.;
RT "Genome sequence of the human- and animal-pathogenic strain Nocardia
RT cyriacigeorgica GUH-2.";
RL J. Bacteriol. 194:2098-2099(2012).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; FO082843; CCF64566.1; -; Genomic_DNA.
DR AlphaFoldDB; H6R4U1; -.
DR STRING; 1127134.NOCYR_3803; -.
DR KEGG; ncy:NOCYR_3803; -.
DR eggNOG; COG1797; Bacteria.
DR HOGENOM; CLU_022752_1_1_11; -.
DR Proteomes; UP000008190; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042242; F:cobyrinic acid a,c-diamide synthase activity; IEA:InterPro.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd03130; GATase1_CobB; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004484; CbiA/CobB_synth.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002586; CobQ/CobB/MinD/ParA_Nub-bd_dom.
DR InterPro; IPR011698; GATase_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43873; COBYRINATE A,C-DIAMIDE SYNTHASE; 1.
DR PANTHER; PTHR43873:SF1; COBYRINATE A,C-DIAMIDE SYNTHASE; 1.
DR Pfam; PF01656; CbiA; 1.
DR Pfam; PF07685; GATase_3; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51274; GATASE_COBBQ; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00022962,
KW ECO:0000256|PROSITE-ProRule:PRU00606};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008190}.
FT DOMAIN 1..177
FT /note="CobQ/CobB/MinD/ParA nucleotide binding"
FT /evidence="ECO:0000259|Pfam:PF01656"
FT DOMAIN 309..470
FT /note="CobB/CobQ-like glutamine amidotransferase"
FT /evidence="ECO:0000259|Pfam:PF07685"
FT REGION 233..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 498 AA; 51383 MW; 67EE09C51B4C61D4 CRC64;
MATGLVGALR RAGHRVAPFK VGPDYIDPGY HGLAAGRPGR NLDPVLCGAE QVVPLYRHGS
AGCDLAVVEG VMGLFDGRID ADDVSPVAEG STAQVAAMLG APVVLVVDAR GHSQSLAALL
HGFATYDSSI RLGGVILNRV GSERHEQVLR AACDRVGLPV LGSLPRMAEL EVPSRHLGLI
PAVEHGAAAT AAVAAMTDLV AAHVDLRAIA ALAASSVTGP AWSPEAALSA GVTREFSRAP
HGTRVNEPDR RAGATTAGSP SEERPLVATT GAGRPTAAED RPGATTGASP VIAMAGGAAF
TFGYAEHREL LVAAGARVEV FDPLHDELPT GTAGLVLPGG FPEEHAADLA ANTRLLDAVA
SAARRGLPIH AECAGLLYLT RSLDGHAMAG VLDATAEFGP RLTLGYRDAV ALSDSPLWRA
GERVHGHEFH RTRLTSTGTD DPAWGWHSAG ARIREGAIVN QVHASYLHTH PAGNPDSVRR
FVTAAAEFAH TDAATRSG
//
