ID H6R806_NOCCG Unreviewed; 340 AA.
AC H6R806;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=(R)-hydratase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=NOCYR_2781 {ECO:0000313|EMBL:CCF63550.1};
OS Nocardia cyriacigeorgica (strain GUH-2).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1127134 {ECO:0000313|EMBL:CCF63550.1, ECO:0000313|Proteomes:UP000008190};
RN [1] {ECO:0000313|EMBL:CCF63550.1, ECO:0000313|Proteomes:UP000008190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GUH-2 {ECO:0000313|EMBL:CCF63550.1,
RC ECO:0000313|Proteomes:UP000008190};
RX PubMed=22461543; DOI=10.1128/JB.00161-12;
RA Zoropogui A., Pujic P., Normand P., Barbe V., Beaman B., Beaman L.,
RA Boiron P., Colinon C., Deredjian A., Graindorge A., Mangenot S.,
RA Nazaret S., Neto M., Petit S., Roche D., Vallenet D., Rodriguez-Nava V.,
RA Richard Y., Cournoyer B., Blaha D.;
RT "Genome sequence of the human- and animal-pathogenic strain Nocardia
RT cyriacigeorgica GUH-2.";
RL J. Bacteriol. 194:2098-2099(2012).
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254}.
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DR EMBL; FO082843; CCF63550.1; -; Genomic_DNA.
DR RefSeq; WP_014351010.1; NC_016887.1.
DR AlphaFoldDB; H6R806; -.
DR STRING; 1127134.NOCYR_2781; -.
DR KEGG; ncy:NOCYR_2781; -.
DR eggNOG; COG2030; Bacteria.
DR HOGENOM; CLU_069117_0_0_11; -.
DR OrthoDB; 5415111at2; -.
DR Proteomes; UP000008190; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProtKB-KW.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR CDD; cd03441; R_hydratase_like; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 2.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR039569; MaoC-like_dehydrat_N.
DR InterPro; IPR002539; MaoC-like_dom.
DR NCBIfam; NF040620; fused_HadA_HadB; 1.
DR PANTHER; PTHR43437; HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43437:SF10; UPF0336 PROTEIN SCO4636; 1.
DR Pfam; PF13452; MaoC_dehydrat_N; 1.
DR Pfam; PF01575; MaoC_dehydratas; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008190}.
FT DOMAIN 11..137
FT /note="N-terminal of MaoC-like dehydratase"
FT /evidence="ECO:0000259|Pfam:PF13452"
FT DOMAIN 212..284
FT /note="MaoC-like"
FT /evidence="ECO:0000259|Pfam:PF01575"
FT REGION 174..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 340 AA; 36687 MW; 76D08E01934BA6A4 CRC64;
MVEAAFDVAG LVGHRYRADD YYEVGREKIR EYARAVQDFH PAHWSEDAAA DLGYTGLLAP
TTFLSTAAML ANRRLLETVM TGFDMFVQTD QVFEMYKPVR TGDRLVSDVE LSSVRRIAGK
DLLTITNTFL DQTGDIVQIM HTTVVGITGE DVSADISDRI ERVVMSGLDT TVRASTAADS
VPEPEPGTRL SPISRTRTPR TEPRFDTVTV GDELPARSVT LTRGDLVNYA GVSGDANPIH
WHEDVAALAG LPDVIAHGML TMGLGAGFVT GWLGDPGALI RYGVRLSNYA IIEADSAGTV
EFTGRIKSLD PETRTAVVVI VAKSGGRKVF GLATADVRLA
//
